Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …

MicroRNAs (miRNAs) repress cellular protein levels to provide a sophisticated parameter of
gene regulation that coordinates a broad spectrum of biological processes. Bone …

Osteoblast differentiation is a multi‐step process where mesenchymal cells differentiate into
osteoblast lineage cells including osteocytes. Osterix (Osx) is an osteoblast‐specific …

The physiological role of microRNAs (miRNAs) in osteoblast differentiation remains elusive.
Exosomal miRNAs isolated from human bone marrow-derived mesenchymal stem cells …

Dysregulation of microRNAs has a critical role in cancer progression. Here we identify an
intronic microRNA, miR-135b that is upregulated in highly invasive non-small-cell lung …

Background: Osteosarcoma is the most common primary malignant bone tumour,
predominantly affecting children and adolescents. Cancer cell line models are required to …

Pathological destructive bone diseases are primarily caused by the failure of a lifelong self‐
renewal process of the skeletal system called bone remodelling. The mechanisms …

Background Diabetes mellitus (DM) is considered to be an important factor for bone
degeneration disorders such as bone defect nonunion, which is characterized by physical …

Bone injury repair has always been a tricky problem in clinic, the recent emergence of bone
tissue engineering provides a new direction for the repair of bone injury. However, some …

miRNAs are endogenously expressed 18-to 25-nucleotide RNAs that regulate gene
expression through translational repression by binding to a target mRNA. Recently, it has …