Environmental determinants of cardiovascular disease

A Bhatnagar - Circulation research, 2017 - Am Heart Assoc
Many features of the environment have been found to exert an important influence on
cardiovascular disease (CVD) risk, progression, and severity. Changes in the environment …

Molecular mechanism involved in cyclophosphamide-induced cardiotoxicity: Old drug with a new vision

A Iqubal, MK Iqubal, S Sharma, MA Ansari, AK Najmi… - Life sciences, 2019 - Elsevier
Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …

Effect of cigarette smoke on gut microbiota: state of knowledge

X Gui, Z Yang, MD Li - Frontiers in Physiology, 2021 - frontiersin.org
Cigarette smoke is a representative source of toxic chemical exposures to humans, and the
adverse consequences of cigarette smoking are mediated by its effect on both neuronal and …

Molecular mechanisms of acrolein toxicity: relevance to human disease

A Moghe, S Ghare, B Lamoreau… - Toxicological …, 2015 - academic.oup.com
Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant
and its potential as a serious environmental health threat is beginning to be recognized …

Impact of electronic cigarettes on the cardiovascular system

H Qasim, ZA Karim, JO Rivera… - Journal of the …, 2017 - Am Heart Assoc
Tobacco smoking is a major public health threat for both smokers and nonsmokers. There is
accumulating evidence demonstrating that smoking causes several human diseases …

Aldehyde detection in electronic cigarette aerosols

MA Ogunwale, M Li, MV Ramakrishnam Raju… - ACS …, 2017 - ACS Publications
Acetaldehyde, acrolein, and formaldehyde are the principal toxic aldehydes present in
cigarette smoke and contribute to the risk of cardiovascular disease and noncancerous …

Electronic cigarettes: a policy statement from the American Heart Association

A Bhatnagar, LP Whitsel, KM Ribisl, C Bullen… - Circulation, 2014 - Am Heart Assoc
For decades, advocacy for tobacco control has been a priority of the American Heart
Association (AHA). In partnership with major public health organizations, the association has …

Molecular mechanisms of aldehyde toxicity: a chemical perspective

RM LoPachin, T Gavin - Chemical research in toxicology, 2014 - ACS Publications
Aldehydes are electrophilic compounds to which humans are pervasively exposed. Despite
a significant health risk due to exposure, the mechanisms of aldehyde toxicity are poorly …

Cardiovascular effects of exposure to cigarette smoke and electronic cigarettes: clinical perspectives from the Prevention of Cardiovascular Disease Section …

PB Morris, BA Ference, E Jahangir, DN Feldman… - Journal of the American …, 2015 - jacc.org
Cardiovascular morbidity and mortality as a result of inhaled tobacco products continues to
be a global healthcare crisis, particularly in low-and middle-income nations lacking the …

Acrolein exposure is associated with increased cardiovascular disease risk

N DeJarnett, DJ Conklin, DW Riggs… - Journal of the …, 2014 - Am Heart Assoc
Background Acrolein is a reactive aldehyde present in high amounts in coal, wood, paper,
and tobacco smoke. It is also generated endogenously by lipid peroxidation and the …