RNA-extraction-free nano-amplified colorimetric test for point-of-care clinical diagnosis of COVID-19

M Alafeef, P Moitra, K Dighe, D Pan - Nature Protocols, 2021 - nature.com
The global pandemic of coronavirus disease 2019 (COVID-19) highlights the shortcomings
of the current testing paradigm for viral disease diagnostics. Here, we report a stepwise …

Recent advances in drug delivery and targeting to the brain

B Sethi, V Kumar, K Mahato, DW Coulter… - Journal of Controlled …, 2022 - Elsevier
Our body keeps separating the toxic chemicals in the blood from the brain. A significant
number of drugs do not enter the central nervous system (CNS) due to the blood-brain …

Unraveling the Fluorescence Mechanism of Carbon Dots with Sub-Single-Particle Resolution

HA Nguyen, I Srivastava, D Pan, M Gruebele - Acs Nano, 2020 - ACS Publications
Unlike quantum dots, photophysical properties of carbon dots (CDs) are not strongly
correlated with particle size. The origin of CD photoluminescence has been related to sp2 …

Nano-enabled sensing approaches for pathogenic bacterial detection

M Alafeef, P Moitra, D Pan - Biosensors and Bioelectronics, 2020 - Elsevier
Infectious diseases caused by pathogenic bacteria, especially antibiotic-resistant bacteria,
are one of the biggest threats to global health. To date, bacterial contamination is detected …

Nucleotide‐driven molecular sensing of monkeypox virus through hierarchical self‐assembly of 2D Hafnium disulfide nanoplatelets and gold nanospheres

P Moitra, M Iftesum, D Skrodzki, P Paul… - Advanced Functional …, 2023 - Wiley Online Library
Liquid interfaces facilitate the organization of nanometer‐scale biomaterials with plasmonic
properties suitable for molecular diagnostics. Using hierarchical assemblage of 2D hafnium …

Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis

X Zhang, SK Misra, P Moitra, X Zhang, SJ Jeong… - Autophagy, 2023 - Taylor & Francis
Dysfunction in the macrophage lysosomal system including reduced acidity and diminished
degradative capacity is a hallmark of atherosclerosis, leading to blunted clearance of excess …

Machine learning for precision breast cancer diagnosis and prediction of the nanoparticle cellular internalization

M Alafeef, I Srivastava, D Pan - ACS sensors, 2020 - ACS Publications
In the field of theranostics, diagnostic nanoparticles are designed to collect highly patient-
selective disease profiles, which is then leveraged by a set of nanotherapeutics to improve …

Physiological and pathological factors affecting drug delivery to the brain by nanoparticles

Y Islam, AG Leach, J Smith, S Pluchino… - Advanced …, 2021 - Wiley Online Library
The prevalence of neurological/neurodegenerative diseases, such as Alzheimer's disease is
known to be increasing due to an aging population and is anticipated to further grow in the …

Influence of electron acceptor and electron donor on the photophysical properties of carbon dots: a comparative investigation at the bulk‐state and single‐particle …

I Srivastava, JS Khamo, S Pandit, P Fathi… - Advanced Functional …, 2019 - Wiley Online Library
Carbon dots (CDs) are extensively studied to investigate their unique optical properties such
as undergoing electron transfer in different scenarios. This work presents an in‐depth …

Hitchhiking probiotic vectors to deliver ultra-small hafnia nanoparticles for 'Color'gastrointestinal tract photon counting X-ray imaging

F Ostadhossein, P Moitra, N Gunaseelan… - Nanoscale …, 2022 - pubs.rsc.org
Gastrointestinal (GI) tract is one of the hard-to-reach target tissues for the delivery of contrast
agents and drugs mediated by nanoparticles due to its harsh environment. Herein, we …