Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan

A Agustí, E Melén, DL DeMeo… - The Lancet …, 2022 - thelancet.com
The traditional view of chronic obstructive pulmonary disease (COPD) as a self-inflicted
disease caused by tobacco smoking in genetically susceptible individuals has been …

Physiological aspects of cardiopulmonary dysanapsis on exercise in adults born preterm

JW Duke, AJ Lewandowski, SH Abman… - The Journal of …, 2022 - Wiley Online Library
Progressive improvements in perinatal care and respiratory management of preterm infants
have resulted in increased survival of newborns of extremely low gestational age over the …

Dysanapsis as a determinant of lung function in development and disease

EA McGinn, EW Mandell, BJ Smith… - American journal of …, 2023 - atsjournals.org
Respiratory diseases in both children and adults are a major cause of morbidity and
mortality worldwide. Despite decades of research, mechanisms underlying the broad …

Pulmonary phenotypes of bronchopulmonary dysplasia in the preterm infant

M Gilfillan, V Bhandari - Seminars in perinatology, 2023 - Elsevier
Bronchopulmonary dysplasia (BPD) remains the most common complication of premature
birth, imposing a significant and potentially life-long burden on patients and their families …

Bronchopulmonary dysplasia as a determinant of respiratory outcomes in adult life

JM Collaco, SA McGrath‐Morrow - Pediatric pulmonology, 2021 - Wiley Online Library
Respiratory disease is unfortunately common in preterm infants with the archetype being
bronchopulmonary dysplasia (BPD). BPD affects approximately 50,000 preterm infants in …

Lung function trajectories in children with post-prematurity respiratory disease: identifying risk factors for abnormal growth

JC Levin, CA Sheils, JM Gaffin, CP Hersh, LM Rhein… - Respiratory …, 2021 - Springer
Background Survivors of prematurity are at risk for abnormal childhood lung function. Few
studies have addressed trajectories of lung function and risk factors for abnormal growth in …

Lung function in adults born preterm

P Näsänen-Gilmore, M Sipola-Leppänen… - PLoS …, 2018 - journals.plos.org
Very preterm birth, before the gestational age (GA) of 32 weeks, increases the risk of
obstructed airflow in adulthood. We examined whether all preterm births (GA< 37 weeks) are …

Established severe BPD: is there a way out? Change of ventilatory paradigms

R Sindelar, EG Shepherd, J Ågren, HB Panitch… - Pediatric …, 2021 - nature.com
Improved survival of extremely preterm newborn infants has increased the number of infants
at risk for developing bronchopulmonary dysplasia (BPD). Despite efforts to prevent BPD …

Respiratory and cardiopulmonary limitations to aerobic exercise capacity in adults born preterm

JW Duke, AT Lovering - Journal of Applied Physiology, 2020 - journals.physiology.org
Adults born preterm, regardless of whether they develop bronchopulmonary dysplasia, have
underdeveloped respiratory and cardiopulmonary systems. The resulting impaired …

Lung function deficits and bronchodilator responsiveness at 12 years of age in children born very preterm compared with controls born at term

C Hagman, LJ Björklund, L Bjermer… - Pediatric …, 2023 - Wiley Online Library
Introduction Very preterm birth is associated with lung function impairment later in life, but
several aspects have not been studied. We aimed to comprehensively assess lung function …