Prevalence and incidence of Huntington's disease: an updated systematic review and meta‐analysis

A Medina, Y Mahjoub, L Shaver… - Movement …, 2022 - Wiley Online Library
The incidence and prevalence of Huntington's disease (HD) based on a systematic review
and meta‐analysis of 20 studies published from 1985 to 2010 was estimated at 0.38 per …

[HTML][HTML] New avenues for the treatment of Huntington's disease

A Kim, K Lalonde, A Truesdell, P Gomes Welter… - International journal of …, 2021 - mdpi.com
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG expansion in
the HD gene. The disease is characterized by neurodegeneration, particularly in the striatum …

[HTML][HTML] Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances

X Niu, J Chen, J Gao - Asian journal of pharmaceutical sciences, 2019 - Elsevier
Neurodegenerative diseases including Alzheimer's disease, Parkinson's disease,
Huntington disease and amyotrophic lateral sclerosis throw a heavy burden on families and …

[HTML][HTML] Huntington disease

NS Caron, GEB Wright, MR Hayden - GeneReviews®[Internet], 2020 - ncbi.nlm.nih.gov
Huntington Disease - GeneReviews® - NCBI Bookshelf US flag An official website of the United
States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …

[HTML][HTML] Nanoparticle-guided brain drug delivery: Expanding the therapeutic approach to neurodegenerative diseases

C Riccardi, F Napolitano, D Montesarchio, S Sampaolo… - Pharmaceutics, 2021 - mdpi.com
Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related
disorders featured by progressive impairment of motor and/or cognitive functions, often …

Prevalence of carriers of intermediate and pathological polyglutamine disease–associated alleles among large population-based cohorts

SL Gardiner, MW Boogaard, S Trompet… - JAMA …, 2019 - jamanetwork.com
Importance Nine hereditary neurodegenerative diseases are known as polyglutamine
diseases, including Huntington disease, 6 spinocerebellar ataxias (SCAs)(SCA1, SCA2 …

[HTML][HTML] Pathogenesis of Huntington's disease: an emphasis on molecular pathways and prevention by natural remedies

Z Irfan, S Khanam, V Karmakar, SM Firdous… - Brain Sciences, 2022 - mdpi.com
Background: Huntington's disease is an inherited autosomal dominant trait neuro-
degenerative disorder caused by changes (mutations) of a gene called huntingtin (htt) that is …

[HTML][HTML] Advances in nanotechnology versus stem cell therapy for the theranostics of Huntington's disease

G Mustafa, D Hassan, M Zeeshan, G Ruiz-Pulido… - Journal of Drug Delivery …, 2023 - Elsevier
Huntington's disease (HD) is a neurological disorder characterized by a reduction in
medium-spiny neurons in the brain. Currently, there is no cure for HD and treatment relies …

Huntington disease: a quarter century of progress since the gene discovery

CM Testa, J Jankovic - Journal of the neurological sciences, 2019 - Elsevier
Huntington disease (HD) is an autosomal dominant neurodegenerative disorder
characterized by motor, behavioral, and cognitive manifestations. It is caused by an …

Huntington disease-like 2: insight into neurodegeneration from an African disease

A Krause, DG Anderson, A Ferreira-Correia… - Nature Reviews …, 2024 - nature.com
Abstract Huntington disease (HD)-like 2 (HDL2) is a rare genetic disease caused by an
expanded trinucleotide repeat in the JPH3 gene (encoding junctophilin 3) that shows …