Human tissue kallikreins (KLKs) are attracting increased attention due to their role as
biomarkers for the screening, diagnosis, prognosis, and monitoring of various cancers …

Sequence-based methods for transcriptome characterization have typically relied on
generation of either serial analysis of gene expression tags or expressed sequence tags …

The Kallikrein-related peptidase (KLK) family consists of fifteen conserved serine proteases
that form the largest contiguous cluster of proteases in the human genome. While primarily …

Purpose The aim of this study was to compare and contrast the expression of all members of
the Kallikrein (KLK) family of genes across 15 cancer types and to evaluate their utility as …

Atherosclerosis preferentially occurs in arterial regions exposed to disturbed blood flow (d-
flow), while regions exposed to stable flow (s-flow) are protected. The proatherogenic and …

Purpose: Our goal was to examine a panel of 11 biochemical variables, measured in
cytosolic extracts of ovarian tissues (normal, benign, and malignant) by quantitative ELISAs …

Background Cancer has remarkable complexity at the molecular level, with multiple genes,
proteins, pathways and regulatory interconnections being affected. We introduce a systems …

The human tissue kallikrein (KLK1) and kallikrein-related peptidases (KLKs) are secreted
serine proteases with diverse expression patterns and physiological roles in different …

One of the challenges of tumour immunology remains the identification of strongly
immunogenic tumour antigens for vaccination. Reverse immunology, that is, the procedure …

Atherosclerotic cardiovascular disease and its complications are a high-incidence disease
worldwide. Numerous studies have shown that blood flow shear has a huge impact on the …