Current state of the art MRI for the longitudinal assessment of cystic fibrosis

JC Woods, JM Wild, MO Wielpütz… - Journal of Magnetic …, 2020 - Wiley Online Library
Pulmonary MRI can now provide high‐resolution images that are sensitive to early disease
and specific to inflammation in cystic fibrosis (CF) lung disease. With specificity and function …

Time to get serious about the detection and monitoring of early lung disease in cystic fibrosis

KJ Bayfield, TA Douglas, T Rosenow, JC Davies… - Thorax, 2021 - thorax.bmj.com
Structural and functional defects within the lungs of children with cystic fibrosis (CF) are
detectable soon after birth and progress throughout preschool years often without overt …

Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report

CCW Hsia, JHT Bates, B Driehuys, SB Fain… - Annals of the …, 2023 - atsjournals.org
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Potential for noninvasive assessment of lung inhomogeneity using highly precise, highly time-resolved measurements of gas exchange

JE Mountain, P Santer, DP O'Neill… - Journal of Applied …, 2018 - journals.physiology.org
Inhomogeneity in the lung impairs gas exchange and can be an early marker of lung
disease. We hypothesized that highly precise measurements of gas exchange contain …

Imaging the injured lung: mechanisms of action and clinical use

M Cereda, Y Xin, A Goffi, J Herrmann, DW Kaczka… - …, 2019 - pubs.asahq.org
Acute respiratory distress syndrome (ARDS) consists of acute hypoxemic respiratory failure
characterized by massive and heterogeneously distributed loss of lung aeration caused by …

[HTML][HTML] A century of exercise physiology: lung fluid balance during and following exercise

G Miserocchi, E Beretta - European Journal of Applied Physiology, 2023 - Springer
Purpose This review recalls the principles developed over a century to describe trans-
capillary fluid exchanges concerning in particular the lung during exercise, a specific …

Measuring lung function in airways diseases: current and emerging techniques

N Petousi, NP Talbot, I Pavord, PA Robbins - Thorax, 2019 - thorax.bmj.com
Chronic airways diseases, including asthma, COPD and cystic fibrosis, cause significant
morbidity and mortality and are associated with high healthcare expenditure, in the UK and …

[HTML][HTML] Ventilation/perfusion relationships and gas exchange: measurement approaches

SR Hopkins - Comprehensive Physiology, 2020 - ncbi.nlm.nih.gov
Abstract Ventilation-perfusion (VA/Q) matching, the regional matching of the flow of fresh gas
to flow of deoxygenated capillary blood, is the most important mechanism affecting the …

Vaping disrupts ventilation-perfusion matching in asymptomatic users

AS Kizhakke Puliyakote, AR Elliott… - Journal of Applied …, 2021 - journals.physiology.org
Inhalation of e-cigarette's aerosols (vaping) has the potential to disrupt pulmonary gas
exchange, but the effects in asymptomatic users are unknown. We assessed ventilation …

Lung functional imaging

S Bayat, J Wild, T Winkler - Breathe, 2023 - Eur Respiratory Soc
Pulmonary functional imaging modalities such as computed tomography, magnetic
resonance imaging and nuclear imaging can quantitatively assess regional lung functional …