Tumourigenesis is the result of cell cycle disorganisation, leading to an uncontrolled cellular
proliferation. Specific cellular processes‐mechanisms that control cell cycle progression and …

The cell cycle The observations of Howard and Pelc, who used 32P incorporation and
autoradiography during the early 1950s, led to the introduction of the concept of the cell …

Purpose: Some studies have described pelvic tumor control and survival rates in invasive
carcinoma of uterine cervix when the overall time in a course of definitive irradiation is …

Twelve published clinical results of radical radiotherapy of head and neck cancer have been
reviewed, seven of them with fresh multivariate analyses, to determine the magnitude of time …

Background Human tumour cells can proliferate rapidly, and giving radiotherapy in many
small fractions may reduce long-term normal-tissue morbidity. In response to these …

A significant effect of treatment duration on pelvic control was found in 830 patients with
cervix cancer treated by radical radiation therapy. Using three methods of analysis, the loss …

Using in vitro established tumour cell lines attempts were made to assess the suitability of
tetrazolium salt reduction (MTT) assay to replace the conventional radioactive base …

Purpose: To analyze the effect of total treatment time on infield pelvic control and survival for
squamous cell carcinoma of the uterine cervix using the combined 1973 and 1978 Patterns …

Purpose: To search for possible influence of overall treatment time on the clinical outcome of
advanced cervical carcinomas treated with radiation alone. Methods and Materials: Three …

Immunohistochemical methods using antibodies to cell cycle-related antigens may be used
as a means of assessing various aspects of proliferation in tissue, and have the important …