Cerebrovascular reactivity (CVR) MRI with CO2 challenge: a technical review

P Liu, B Jill, H Lu - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …

Cerebrovascular reactivity measurement using magnetic resonance imaging: a systematic review

E Sleight, MS Stringer, I Marshall, JM Wardlaw… - Frontiers in …, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) magnetic resonance imaging (MRI) probes cerebral
haemodynamic changes in response to a vasodilatory stimulus. CVR closely relates to the …

Cerebrovascular reactivity mapping without gas challenges: a methodological guide

J Pinto, MG Bright, DP Bulte, P Figueiredo - Frontiers in Physiology, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) is defined as the ability of vessels to alter their caliber in
response to vasoactive factors, by means of dilating or constricting, in order to increase or …

Vascular smooth muscle cell dysfunction in neurodegeneration

G Hayes, J Pinto, SN Sparks, C Wang, S Suri… - Frontiers in …, 2022 - frontiersin.org
Vascular smooth muscle cells (VSMCs) are the key moderators of cerebrovascular dynamics
in response to the brain's oxygen and nutrient demands. Crucially, VSMCs may provide a …

Magnetic resonance imaging–based cerebrovascular reactivity and hemodynamic reserve: a review of method optimization and data interpretation

JA Fisher, L Venkatraghavan, DJ Mikulis - Stroke, 2018 - Am Heart Assoc
Given adequate perfusion pressure and nonlimiting intracranial or venous pressure,
cerebral blood flow (CBF) is regulated to match cerebral metabolic rate of oxygen (CMRO2) …

Neuroimaging assessment of cerebrovascular reactivity in concussion: current concepts, methodological considerations, and review of the literature

MJ Ellis, LN Ryner, O Sobczyk, J Fierstra… - Frontiers in …, 2016 - frontiersin.org
Concussion is a form of traumatic brain injury (TBI) that presents with a wide spectrum of
subjective symptoms and few objective clinical findings. Emerging research suggests that …

Comparing cerebrovascular reactivity measured using BOLD and cerebral blood flow MRI: The effect of basal vascular tension on vasodilatory and vasoconstrictive …

S Halani, JB Kwinta, AM Golestani, YB Khatamian… - Neuroimage, 2015 - Elsevier
Cerebrovascular reactivity (CVR) is an important metric of cerebrovascular health. While the
BOLD fMRI method in conjunction with carbon-dioxide (CO 2) based vascular manipulation …

Magnetic resonance imaging for assessment of cerebrovascular reactivity in cerebral small vessel disease: a systematic review

GW Blair, FN Doubal, MJ Thrippleton… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral small vessel disease (SVD) pathophysiology is poorly understood.
Cerebrovascular reactivity (CVR) impairment may play a role, but evidence to date is mainly …

Association of cerebrovascular reactivity and Alzheimer pathologic markers with cognitive performance

S Sur, Z Lin, Y Li, S Yasar, P Rosenberg, A Moghekar… - Neurology, 2020 - AAN Enterprises
Objective To determine whether MRI-based cerebrovascular reactivity (CVR) can predict
cognitive performance independently of Alzheimer pathologic markers, we studied the …

Neuroimaging of vascular reserve in patients with cerebrovascular diseases

MR Juttukonda, MJ Donahue - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity, defined broadly as the ability of brain parenchyma to adjust
cerebral blood flow in response to altered metabolic demand or a vasoactive stimulus, is …