Cannabinoids as anticancer drugs: current status of preclinical research
B Hinz, R Ramer - British journal of cancer, 2022 - nature.com
Drugs that target the endocannabinoid system are of interest as pharmacological options to
combat cancer and to improve the life quality of cancer patients. From this perspective …
combat cancer and to improve the life quality of cancer patients. From this perspective …
Cannabidiol: State of the art and new challenges for therapeutic applications
Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …
The role of hypoxia in glioblastoma invasion
AR Monteiro, R Hill, GJ Pilkington, PA Madureira - Cells, 2017 - mdpi.com
Glioblastoma multiforme (GBM), a grade IV astrocytoma, is the most common and deadly
type of primary malignant brain tumor, with a patient's median survival rate ranging from 15 …
type of primary malignant brain tumor, with a patient's median survival rate ranging from 15 …
[HTML][HTML] Anticancer mechanisms of cannabinoids
In addition to the well-known palliative effects of cannabinoids on some cancer-associated
symptoms, a large body of evidence shows that these molecules can decrease tumour …
symptoms, a large body of evidence shows that these molecules can decrease tumour …
The endocannabinoid system: A target for cancer treatment
In recent years, the endocannabinoid system has received great interest as a potential
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …
The ID proteins: master regulators of cancer stem cells and tumour aggressiveness
A Lasorella, R Benezra, A Iavarone - Nature Reviews Cancer, 2014 - nature.com
Inhibitor of DNA binding (ID) proteins are transcriptional regulators that control the timing of
cell fate determination and differentiation in stem and progenitor cells during normal …
cell fate determination and differentiation in stem and progenitor cells during normal …
Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma
E Singer, J Judkins, N Salomonis, L Matlaf… - Cell death & …, 2015 - nature.com
Glioblastoma (GBM) resistance to therapy is the most common cause of tumor recurrence,
which is ultimately fatal in 90% of the patients 5 years after initial diagnosis. A sub …
which is ultimately fatal in 90% of the patients 5 years after initial diagnosis. A sub …
[HTML][HTML] Cannabinoids as therapeutic agents in cancer: current status and future implications
B Chakravarti, J Ravi, RK Ganju - Oncotarget, 2014 - ncbi.nlm.nih.gov
The pharmacological importance of cannabinoids has been in study for several years.
Cannabinoids comprise of (a) the active compounds of the Cannabis sativa plant,(b) …
Cannabinoids comprise of (a) the active compounds of the Cannabis sativa plant,(b) …
Anti‐tumour actions of cannabinoids
B Hinz, R Ramer - British journal of pharmacology, 2019 - Wiley Online Library
The endocannabinoid system has emerged as an important target for the treatment of many
diverse diseases. In addition to the well‐established palliative effects of cannabinoids in …
diverse diseases. In addition to the well‐established palliative effects of cannabinoids in …
Glioblastoma stem-like cells: at the root of tumor recurrence and a therapeutic target
M Jackson, F Hassiotou, A Nowak - Carcinogenesis, 2015 - academic.oup.com
Glioblastoma is the most common and most aggressive primary brain malignancy. The
current initial standard of care consists of maximal safe surgical resection followed by radical …
current initial standard of care consists of maximal safe surgical resection followed by radical …