Human iPSC-derived glia models for the study of neuroinflammation
N Stöberl, E Maguire, E Salis, B Shaw… - Journal of …, 2023 - Springer
Neuroinflammation is a complex biological process that plays a significant role in various
brain disorders. Microglia and astrocytes are the key cell types involved in inflammatory …
brain disorders. Microglia and astrocytes are the key cell types involved in inflammatory …
Neuroimmune mechanisms of opioid use disorder and recovery: Translatability to human studies, and future research directions
ER Butelman, RZ Goldstein, CA Nwaneshiudu… - Neuroscience, 2023 - Elsevier
Opioid use disorder (OUD) is a major current cause of morbidity and mortality. Long-term
exposure to short-acting opioids (MOP-r agonists such as heroin or fentanyl) results in …
exposure to short-acting opioids (MOP-r agonists such as heroin or fentanyl) results in …
[HTML][HTML] In vivo photopharmacology with light-activated opioid drugs
SP McClain, X Ma, DA Johnson, CA Johnson… - Neuron, 2023 - cell.com
Traditional methods for site-specific drug delivery in the brain are slow, invasive, and difficult
to interface with recordings of neural activity. Here, we demonstrate the feasibility and …
to interface with recordings of neural activity. Here, we demonstrate the feasibility and …
[HTML][HTML] Melatonin, BAG-1 and cortisol circadian interactions in tumor pathogenesis and patterned immune responses
G Anderson - Exploration of targeted anti-tumor therapy, 2023 - ncbi.nlm.nih.gov
A dysregulated circadian rhythm is significantly associated with cancer risk, as is aging. Both
aging and circadian dysregulation show suppressed pineal melatonin, which is indicated in …
aging and circadian dysregulation show suppressed pineal melatonin, which is indicated in …
[HTML][HTML] Mechanism of baixiangdan capsules on anti-neuroinflammation: combining dry and wet experiments
Q Yu, M Liu, T Zhao, M Su, S Wang, W Xu, S He… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Neuroinflammation plays an important role in the pathogenesis of neurological disorders,
and despite intensive research, treatment of neuroinflammation remains limited …
and despite intensive research, treatment of neuroinflammation remains limited …
Unveiling the link between chronic pain and misuse of opioids and cannabis
Over 50 million Americans endure chronic pain where many do not receive adequate
treatment and self-medicate to manage their pain by taking substances like opioids and …
treatment and self-medicate to manage their pain by taking substances like opioids and …
Amelioration of morphine withdrawal syndrome by systemic and intranasal administration of mesenchymal stem cell‐derived secretome in preclinical models of …
M Quezada, C Ponce… - CNS Neuroscience …, 2024 - Wiley Online Library
Background Morphine is an opiate commonly used in the treatment of moderate to severe
pain. However, prolonged administration can lead to physical dependence and strong …
pain. However, prolonged administration can lead to physical dependence and strong …
Neuroinflammation drives sex-dependent effects on pain and negative affect in a murine model of repeated mild traumatic brain injury
SS Liu, S Pickens, Z Barta, M Rice, M Dagher… - Pain, 2022 - journals.lww.com
Abstract The Center for Disease Control and Prevention estimates that 75% of reported
cases of traumatic brain injury (TBI) are mild, where chronic pain and depression are 2 of the …
cases of traumatic brain injury (TBI) are mild, where chronic pain and depression are 2 of the …
How omics is revealing new roles for glia in addiction
DJ Bergkamp, JF Neumaier - Glia - Wiley Online Library
Experiments to study the biology of addiction have historically focused on the mechanisms
through which drugs of abuse drive changes in the functioning of neurons and neural …
through which drugs of abuse drive changes in the functioning of neurons and neural …
Role of Astrocytic µ-Opioid Receptors in Neuroinflammation
D Tang - 2024 - search.proquest.com
Many neurological disorders are associated with neuroinflammation. Glial cells, including
astrocytes, are the primary brain cells involved in the mechanisms of neuroinflammation …
astrocytes, are the primary brain cells involved in the mechanisms of neuroinflammation …