Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention
Abstract Endocrine Disrupting Chemicals (EDCs) are a global problem for environmental
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …
Metabolism and metabolites of polychlorinated biphenyls
FA Grimm, D Hu, I Kania-Korwel… - Critical reviews in …, 2015 - Taylor & Francis
The metabolism of polychlorinated biphenyls (PCBs) is complex and has an impact on
toxicity, and thereby on the assessment of PCB risks. A large number of reactive and stable …
toxicity, and thereby on the assessment of PCB risks. A large number of reactive and stable …
Endocrine-disrupting chemicals: an Endocrine Society scientific statement
E Diamanti-Kandarakis, JP Bourguignon… - Endocrine …, 2009 - academic.oup.com
There is growing interest in the possible health threat posed by endocrine-disrupting
chemicals (EDCs), which are substances in our environment, food, and consumer products …
chemicals (EDCs), which are substances in our environment, food, and consumer products …
Risk for animal and human health related to the presence of dioxins and dioxin‐like PCBs in feed and food
EFSA Panel on Contaminants in the Food Chain … - Efsa …, 2018 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific opinion on the risks for
animal and human health related to the presence of dioxins (PCDD/Fs) and DL‐PCBs in …
animal and human health related to the presence of dioxins (PCDD/Fs) and DL‐PCBs in …
Effects of developmental exposure to 2, 2′, 4, 4′, 5-pentabromodiphenyl ether (PBDE-99) on sex steroids, sexual development, and sexually dimorphic behavior in …
H Lilienthal, A Hack, A Roth-Härer… - Environmental …, 2006 - ehp.niehs.nih.gov
Increasing concentrations of polybrominated flame retardants, including polybrominated
diphenyl ethers (PBDEs), in breast milk cause concern about possible developmental effects …
diphenyl ethers (PBDEs), in breast milk cause concern about possible developmental effects …
Endocrine-disrupting chemicals and autoimmune diseases
RG Huang, XB Li, YY Wang, H Wu, KD Li, X Jin… - Environmental …, 2023 - Elsevier
Endocrine-disrupting chemicals (EDCs) widely exist in people's production and life which
have great potential to damage human and animal health. Over the past few decades …
have great potential to damage human and animal health. Over the past few decades …
Effects of perinatal PBDE exposure on hepatic phase I, phase II, phase III, and deiodinase 1 gene expression involved in thyroid hormone metabolism in male rat pups
DT Szabo, VM Richardson, DG Ross… - Toxicological …, 2009 - academic.oup.com
Previous studies demonstrated that perinatal exposure to polybrominated diphenyl ethers
(PBDEs), a major class of brominated flame retardants, may affect thyroid hormone (TH) …
(PBDEs), a major class of brominated flame retardants, may affect thyroid hormone (TH) …
Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener
VM Richardson, DF Staskal, DG Ross… - Toxicology and applied …, 2008 - Elsevier
Polybrominated diphenyl ethers (PBDEs) are a class of polyhalogenated aromatic
compounds commercially used as fire retardants in consumer products. These compounds …
compounds commercially used as fire retardants in consumer products. These compounds …
[HTML][HTML] Critical comments on the WHO-UNEP State of the Science of Endocrine Disrupting Chemicals–2012
JC Lamb IV, P Boffetta, WG Foster, JE Goodman… - Regulatory Toxicology …, 2014 - Elsevier
Abstract Early in 2013, the World Health Organization (WHO) released a 2012 update to the
2002 State of the Science of Endocrine Disrupting Chemicals. Several significant concerns …
2002 State of the Science of Endocrine Disrupting Chemicals. Several significant concerns …
Exposure to tetrabromobisphenol A (TBBPA) in Wistar rats: neurobehavioral effects in offspring from a one-generation reproduction study
H Lilienthal, CM Verwer, LTM van der Ven, AH Piersma… - Toxicology, 2008 - Elsevier
Within the framework of an EU project on risk assessment of brominated flame retardants,
TBBPA was studied for neurobehavioral effects in rats. To permit benchmark dose analysis …
TBBPA was studied for neurobehavioral effects in rats. To permit benchmark dose analysis …