The interest in functional supramolecular systems for the design of innovative materials and
technologies, able to fundamentally change the world, is growing at a high pace. The huge …

Peroxiredoxins (Prxs) constitute a major family of peroxidases, with mammalian cells
expressing six Prx isoforms (PrxI to PrxVI). Cells produce hydrogen peroxide (H2O2) at …

Peroxiredoxins (Prdxs) sense and assess peroxide levels, and signal through protein
interactions. Understanding the role of the multiple structural and post-translational …

Mitochondrial quality control (MQC) consists of multiple processes: the prevention of
mitochondrial oxidative damage, the elimination of damaged mitochondria via mitophagy …

Protein capsids are specialized and versatile natural macromolecules with exceptional
properties. Their homogenous, spherical, rod‐like or toroidal geometry, and spatially …

Aims: Mitochondrial dysfunction is the primary mechanism of liver ischemia/reperfusion (I/R)
injury. The lysine desuccinylase sirtuin 5 (SIRT5) is a global regulator of the mitochondrial …

Mitochondria are main sites of peroxynitrite formation. While at low concentrations
mitochondrial peroxynitrite has been associated with redox signaling actions, increased …

Abstract Peroxiredoxin 3 (PRDX3) belongs to a superfamily of peroxidases that function as
protective antioxidant enzymes. Among the six isoforms (PRDX1–PRDX6), PRDX3 is the …

Abstract Peroxiredoxin 3 (PRDX3) encodes a mitochondrial antioxidant protein, which is
essential for the control of reactive oxygen species homeostasis. So far, PRDX3 mutations …

Enhanced production of reactive oxygen species (ROS) triggered by various stimuli,
including viral infections, has attributed much attention in the past years. It has been shown …