Systematic interrogation of human promoters

S Weingarten-Gabbay, R Nir, S Lubliner… - Genome …, 2019 - genome.cshlp.org
Despite much research, our understanding of the architecture and cis-regulatory elements of
human promoters is still lacking. Here, we devised a high-throughput assay to quantify the …

iEnhancer-DCSV: Predicting enhancers and their strength based on DenseNet and improved convolutional block attention module

J Jia, R Lei, L Qin, G Wu, X Wei - Frontiers in Genetics, 2023 - frontiersin.org
Enhancers play a crucial role in controlling gene transcription and expression. Therefore,
bioinformatics puts many emphases on predicting enhancers and their strength. It is vital to …

iPro2L-DG: Hybrid network based on improved densenet and global attention mechanism for identifying promoter sequences

R Lei, J Jia, L Qin, X Wei - Heliyon, 2024 - cell.com
The promoter is a key DNA sequence whose primary function is to control the initiation time
and the degree of expression of gene transcription. Accurate identification of promoters is …

[HTML][HTML] Molecular Cloning and Functional Characterization of a Cytochrome P450 Enzyme (SaCYP736A167) Promoter from Santalum album

H Yan, Y Zhang, R Wei, L Qiu, H Zhou, F Xiong, G Ma - Forests, 2024 - mdpi.com
The primary constituents of the essential oil derived from Santalum album L. are (Z)-α-
santalol,(Z)-β-santalol,(Z)-α-exo-bergamotol, and (Z)-epi-β-santalol. SaCYP736A167 plays a …

Molecular Cloning and Functional Characterization of Bisabolene Synthetase (SaBS) Promoter from Santalum album

H Yan, Y Xiong, JA Teixeira da Silva, J Pang, T Zhang… - Forests, 2020 - mdpi.com
Bisabolene-type sesquiterpenoids, which have multiple bioactivities, including anticancer
activity, are one of the main groups of compounds in the essential oil extracted from …

Insights into ACO genes across Rosaceae: evolution, expression, and regulatory networks in fruit development

Y Zhang, Y Zhang, Z Yu, H Wang, B Ping, Y Liu… - Genes & Genomics, 2024 - Springer
Abstract Background ACO (1-aminocyclopropane-1-carboxylic acid) serves as a pivotal
enzyme within the plant ethylene synthesis pathway, exerting influence over critical facets of …

[图书][B] Methods in computational genomics

N Olson, L Chen - 2024 - books.google.com
Genes are functional areas of an organism's DNA (Dai et al., 2018; Kong et al., 2020) that
hold genetic information. The gene is transferred to the protein through a sequence of …

Using RAMPAGE to identify and annotate promoters in insect genomes

RT Raborn, VP Brendel - Insect Genomics: Methods and Protocols, 2019 - Springer
Abstract Application of Transcription Start Site (TSS) profiling technologies, coupled with
large-scale next-generation sequencing (NGS) has yielded valuable insights into the …

Cloning and functional analysis of the promoter of SinSyn gene in Sinomenium acutum

M An, B Li, J Chen, X Zeng, X Chen, H Yang - 2024 - researchsquare.com
Sinoacutine synthetase (SinSyn) is one of the key enzymes in the biosynthesis pathway of
sinomenine (SIN), an effective pharmacological component in Sinomenium acutum …

Deciphering transcriptional regulation of human core promoters

S Weingarten-Gabbay, R Nir, S Lubliner, E Sharon… - bioRxiv, 2017 - biorxiv.org
Although traditionally viewed as universal stretches of DNA, core promoters are diverse
regulatory sequences with a high impact on transcriptional activity in promoters and …