Ferroptosis and its emerging roles in cardiovascular diseases
N Li, W Jiang, W Wang, R Xiong, X Wu… - Pharmacological Research, 2021 - Elsevier
Ferroptosis is a new form of regulated cell death (RCD) driven by iron-dependent lipid
peroxidation, which is morphologically and mechanistically distinct from other forms of RCD …
peroxidation, which is morphologically and mechanistically distinct from other forms of RCD …
[HTML][HTML] Mechanistic concepts of iron-sulfur protein biogenesis in Biology
JJ Braymer, SA Freibert, M Rakwalska-Bange… - Biochimica et Biophysica …, 2021 - Elsevier
Abstract Iron-sulfur (Fe/S) proteins are present in virtually all living organisms and are
involved in numerous cellular processes such as respiration, photosynthesis, metabolic …
involved in numerous cellular processes such as respiration, photosynthesis, metabolic …
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway
GH Chen, CC Song, K Pantopoulos, XL Wei… - Free Radical Biology …, 2022 - Elsevier
Ferroptosis is a regulated form of cell death induced by iron (Fe)-dependent lipid
peroxidation. At present, the underlying molecular mechanisms remain elusive. Herein, we …
peroxidation. At present, the underlying molecular mechanisms remain elusive. Herein, we …
Iron and cancer: 2020 vision
SV Torti, FM Torti - Cancer research, 2020 - AACR
New and provocative insights into the relationships between iron and cancer have been
uncovered in recent years. These include delineation of connections that link cellular iron to …
uncovered in recent years. These include delineation of connections that link cellular iron to …
Iron homeostasis and organismal aging
Iron is indispensable for normal body functions across species because of its critical roles in
red blood cell function and many essential proteins and enzymes required for numerous …
red blood cell function and many essential proteins and enzymes required for numerous …
miR‐29a‐3p in Exosomes from Heme Oxygenase‐1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia‐Reperfusion Injury in Rats …
X Li, L Wu, X Tian, W Zheng, M Yuan… - Oxidative Medicine …, 2022 - Wiley Online Library
Hepatic ischemia‐reperfusion injury (IRI) is an inevitable result of liver surgery. Steatotic
livers are extremely sensitive to IRI and have worse tolerance. Ferroptosis is considered to …
livers are extremely sensitive to IRI and have worse tolerance. Ferroptosis is considered to …
Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus
X Gao, Y Song, J Wu, S Lu, X Min, L Liu… - The Journal of …, 2022 - Am Soc Clin Investig
The trace element iron affects immune responses and vaccination, but knowledge of its role
in autoimmune diseases is limited. Expansion of pathogenic T cells, especially T follicular …
in autoimmune diseases is limited. Expansion of pathogenic T cells, especially T follicular …
Nutritional aspects of iron in health and disease
E Charlebois, K Pantopoulos - Nutrients, 2023 - mdpi.com
Dietary iron assimilation is critical for health and essential to prevent iron-deficient states
and related comorbidities, such as anemia. The bioavailability of iron is generally low, while …
and related comorbidities, such as anemia. The bioavailability of iron is generally low, while …
The calcium–iron connection in ferroptosis-mediated neuronal death
S Gleitze, A Paula-Lima, MT Núñez… - Free Radical Biology and …, 2021 - Elsevier
Iron, through its participation in oxidation/reduction processes, is essential for the
physiological function of biological systems. In the brain, iron is involved in the development …
physiological function of biological systems. In the brain, iron is involved in the development …
[HTML][HTML] Emerging mechanisms and targeted therapy of ferroptosis in neurological diseases and neuro-oncology
Y Wang, B Tang, J Zhu, J Yu, J Hui… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Ferroptosis is a novel type of cell death characterized by iron-dependent lipid peroxidation
that involves a variety of biological processes, such as iron metabolism, lipid metabolism …
that involves a variety of biological processes, such as iron metabolism, lipid metabolism …