Effects and mechanisms of natural alkaloids for prevention and treatment of osteoporosis
B Lin, P Xu, J Zheng, X Deng, Q Ye, Z Huang… - Frontiers in …, 2022 - frontiersin.org
Natural alkaloids are polycyclic, nitrogen-containing, and basic compounds obtained from
plants. In this review, the advances in bioactive alkaloids with respect to their chemical …
plants. In this review, the advances in bioactive alkaloids with respect to their chemical …
A paradoxical role for sestrin 2 protein in tumor suppression and tumorigenesis
J Qu, M Luo, J Zhang, F Han, N Hou, R Pan… - Cancer Cell …, 2021 - Springer
Sestrin 2, a highly conserved stress-induced protein, participates in the pathological
processes of metabolic and age-related diseases. This p53-inducible protein also regulates …
processes of metabolic and age-related diseases. This p53-inducible protein also regulates …
Notopterol Attenuates Estrogen Deficiency-Induced Osteoporosis via Repressing RANKL Signaling and Reactive Oxygen Species
D Chen, Q Wang, Y Li, P Sun, V Kuek, J Yuan… - Frontiers in …, 2021 - frontiersin.org
Integrity of the skeleton is sustained through the balanced activities of osteoblasts and
osteoclasts in bone remodeling unit. The balance can be disrupted by excessive osteoclasts …
osteoclasts in bone remodeling unit. The balance can be disrupted by excessive osteoclasts …
Isoquercitrin attenuates the osteoclast-mediated bone loss in rheumatoid arthritis via the Nrf2/ROS/NF-κB pathway
Y Liu, T Li, J Bai, W Liu, Z Wang, C Feng, L Pu… - … et Biophysica Acta (BBA …, 2024 - Elsevier
An excess of osteoclastogenesis significantly contributes to the development of rheumatoid
arthritis (RA). Activation of the nuclear factor erythroid-2 related factor 2 (Nrf2) and nuclear …
arthritis (RA). Activation of the nuclear factor erythroid-2 related factor 2 (Nrf2) and nuclear …
Ellagic acid blocks RANKL–RANK interaction and suppresses RANKL-induced osteoclastogenesis by inhibiting RANK signaling pathways
H Xu, F Chen, T Liu, J Xu, J Li, L Jiang, X Wang… - Chemico-Biological …, 2020 - Elsevier
Ellagic acid (EA) is a naturally occurring polyphenolic compound that has been shown to
exhibit diverse beneficial pharmacological activities including anti-osteoclastogenesis effect …
exhibit diverse beneficial pharmacological activities including anti-osteoclastogenesis effect …
[HTML][HTML] Multifunctional nanomaterials via cell cuproptosis and oxidative stress for treating osteosarcoma and OS-induced bone destruction
L Ye, C Yu, J Xia, K Ni, Y Zhang, X Ying, D Xie, Y Jin… - Materials Today Bio, 2024 - Elsevier
Abstract Reactive Oxygen Species (ROS) refers to a highly reactive class of oxidizing
species that have the potential to induce cellular apoptosis and necrosis. Cuproptosis, a …
species that have the potential to induce cellular apoptosis and necrosis. Cuproptosis, a …
Periplogenin attenuates LPS-mediated inflammatory osteolysis through the suppression of osteoclastogenesis via reducing the NF-κB and MAPK signaling pathways
K Gan, H Lian, T Yang, J Huang, J Chen, Y Su… - Cell Death …, 2024 - nature.com
The key target for treating inflammatory osteolysis is osteoclasts. In an inflammatory
environment, osteoclast differentiation increases, and bone resorption is enhanced …
environment, osteoclast differentiation increases, and bone resorption is enhanced …
Novel Aurora A Kinase Inhibitor Fangchinoline Enhances Cisplatin–DNA Adducts and Cisplatin Therapeutic Efficacy in OVCAR-3 Ovarian Cancer Cells-Derived …
D Winardi, PY Chu, GY Chen, K Wang, WY Hsu… - International Journal of …, 2022 - mdpi.com
Aurora A kinase (Aurora A) is a serine/threonine kinase regulating control of multiple events
during cell-cycle progression. Playing roles in promoting proliferation and inhibiting cell …
during cell-cycle progression. Playing roles in promoting proliferation and inhibiting cell …
Absorption and transport properties of a codfish-derived peptide and its protective effect on bone loss in ovariectomized mice
M Yang, S Su, S Cheng, Z Wang, M Du - Food & Function, 2024 - pubs.rsc.org
A potential osteogenic tetradecapeptide with the amino acid sequence GETNPADSKPGSIR
(P-GM-2) was identified from Gadus morhua. The present study aimed to elucidate its …
(P-GM-2) was identified from Gadus morhua. The present study aimed to elucidate its …
[HTML][HTML] In silico network analysis of ingredients of Cornus officinalis in osteoporosis
F Huang, H Guo, Y Wei, X Zhao, Y Chen… - … Medical Journal of …, 2021 - ncbi.nlm.nih.gov
In Silico Network Analysis of Ingredients of Cornus officinalis in Osteoporosis - PMC Back to
Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …
Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …