The addition of cyanide to a carbonyl compound to form a cyanohydrin is one of the
fundamental carbon-carbon bond forming reactions in organic chemistry1 and has …

Lyases are enzymes that catalyze the bond construction and breaking by means other than
hydrolysis or redox reactions. Such enzymes are particular in the sense that they only …

Methods for the catalytic asymmetric synthesis of cyanohydrins derived from both aldehydes
and ketones are reviewed. Successful catalysts based on enzymes, peptides and …

3.2 Glycosyltransferases 3.3 Other carbohydrate processing enzymes 4 Other hydrolytic
enzymes 4.1 Epoxidases 4.2 Nitrilases and nitrile hydratases 4.3 Other hydrolases 5 …

An important class of compounds which can be produced by means of enzymatic routes are
enantiomerically pure aromatic α‐hydroxy carboxylic acids, in particular mandelic acid and …

The application of hydroxynitrile lyases (HNLs) as catalysts for the stereoselective
condensation of HCN with carbonyl compounds has been reported as early as 1908. This …

Biobased raw materials, such as carbohydrates, amino acids, nucleotides, or lipids contain
valuable functional groups with oxygen and nitrogen atoms. An abundance of many …

Oxynitrilases are enzymes which catalyse the formation and cleavage of cyanohydrins. The
cyanohydrin formation reaction proceeds by stereoselective addition of hydrogen cyanide to …

Of all the types of enzyme-catalyzed reactions, hydrolytic transformations involving amide
and ester bonds are the easiest to perform using proteases, esterases, or lipases. The key …

Sažetak We review the state of the art regarding the application of hydroxynitrile lyases to
obtain, enantioselectively,(R)-and (S)-cyanohydrins of aldehydes and ketones. Special …