Chasing bacterial chassis for metabolic engineering: a perspective review from classical to non‐traditional microorganisms
The last few years have witnessed an unprecedented increase in the number of novel
bacterial species that hold potential to be used for metabolic engineering. Historically …
bacterial species that hold potential to be used for metabolic engineering. Historically …
SWATH‐MS as a tool for biomarker discovery: From basic research to clinical applications
In the era of quantitative proteomics, where mass spectrometry plays a pivotal role, in
particular associated with the use of data‐independent acquisition, it is time to perform an …
particular associated with the use of data‐independent acquisition, it is time to perform an …
[HTML][HTML] Systematic overexpression study to find target enzymes enhancing production of terpenes in Synechocystis PCC 6803, using isoprene as a model compound
Of the two natural metabolic pathways for making terpenoids, biotechnological utilization of
the mevalonate (MVA) pathway has enabled commercial production of valuable …
the mevalonate (MVA) pathway has enabled commercial production of valuable …
A squalene synthase protein degradation method for improved sesquiterpene production in Saccharomyces cerevisiae
B Peng, MR Plan, P Chrysanthopoulos, MP Hodson… - Metabolic …, 2017 - Elsevier
Sesquiterpenes are C15 isoprenoids with utility as fragrances, flavours, pharmaceuticals,
and potential biofuels. Microbial fermentation is being examined as a competitive approach …
and potential biofuels. Microbial fermentation is being examined as a competitive approach …
Extrachromosomal Genetic Engineering of the Marine Diatom Phaeodactylum tricornutum Enables the Heterologous Production of Monoterpenoids
Geraniol is a commercially relevant plant-derived monoterpenoid that is a main component
of rose essential oil and used as insect repellent. Geraniol is also a key intermediate …
of rose essential oil and used as insect repellent. Geraniol is also a key intermediate …
[HTML][HTML] Terpenoid metabolic engineering in photosynthetic microorganisms
Terpenoids are a group of natural products that have a variety of essential and non-essential
roles in metabolism, in biotic and abiotic interactions, as well as commercial applications …
roles in metabolism, in biotic and abiotic interactions, as well as commercial applications …
[HTML][HTML] High density cultivation for efficient sesquiterpenoid biosynthesis in Synechocystis sp. PCC 6803
D Dienst, J Wichmann, O Mantovani, JS Rodrigues… - Scientific reports, 2020 - nature.com
Cyanobacteria and microalgae are attractive photoautotrophic host systems for climate-
friendly production of fuels and other value-added biochemicals. However, for economic …
friendly production of fuels and other value-added biochemicals. However, for economic …
[HTML][HTML] Investigation of the methylerythritol 4-phosphate pathway for microbial terpenoid production through metabolic control analysis
Background Terpenoids are of high interest as chemical building blocks and
pharmaceuticals. In microbes, terpenoids can be synthesized via the methylerythritol …
pharmaceuticals. In microbes, terpenoids can be synthesized via the methylerythritol …
Start-Stop Assembly: a functionally scarless DNA assembly system optimized for metabolic engineering
DNA assembly allows individual DNA constructs or libraries to be assembled quickly and
reliably. Most methods are either:(i) Modular, easily scalable and suitable for combinatorial …
reliably. Most methods are either:(i) Modular, easily scalable and suitable for combinatorial …
[HTML][HTML] Metabolic Engineering Escherichia coli for the Production of Lycopene
Z Wang, JX Sun, Q Yang, J Yang - Molecules, 2020 - mdpi.com
Lycopene, a potent antioxidant, has been widely used in the fields of pharmaceuticals,
nutraceuticals, and cosmetics. However, the production of lycopene extracted from natural …
nutraceuticals, and cosmetics. However, the production of lycopene extracted from natural …