Suppression of antitumor immune responses is one of the main mechanisms by which tumor
cells escape from destruction by the immune system. Myeloid-derived suppressor cells …

Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …

Radio-and chemotherapy are the most common cancer treatment modalities. They cause
acute and late side effects on normal tissues, which is a burden for delivery of a high dose of …

With a constantly increasing incidence, cutaneous melanoma has raised the need for a
better understanding of its complex microenvironment that may further guide therapeutic …

Simple Summary Melanoma is a devastating skin cancer characterized by an impressive
metabolic plasticity. Melanoma cells are able to adapt to the tumor microenvironment by …

Background The resistance to PD-1/PD-L1 inhibitors for the treatment of melanoma have
prompted investigators to implement novel clinical trials which combine immunotherapy with …

In agreement with the neurodevelopmental hypothesis of schizophrenia, prenatal exposure
of rats to the antimitotic agent methylazoxymethanol acetate (MAM) at gestational day 17 …

Photosensitivity to structurally diverse drugs is a common but under-reported adverse
cutaneous reaction and can be classified as phototoxic or photoallergic. Phototoxic …

This review aims to explore applied variety methods for prognosis and diagnosis melanoma
in early stages. The role of skin self-examination in early detection, the use of dreamscape …

Anti–programmed cell death protein‐1 (anti‐PD‐1) therapy has greatly improved outcomes
of patients with melanoma; however, many fail to respond. Although preclinical studies …