Numerous drug treatments that have recently entered the clinic or clinical trials have their
genesis in zebrafish. Zebrafish are well established for their contribution to developmental …

Image-based profiling is a maturing strategy by which the rich information present in
biological images is reduced to a multidimensional profile, a collection of extracted image …

Unpredicted human safety events in clinical trials for new drugs are costly in terms of human
health and money. The drug discovery industry attempts to minimize those events with …

Biomarkers have transformed modern medicine but remain largely elusive in psychiatry,
partly because there is a weak correspondence between diagnostic labels and their …

This study investigated the direct and indirect toxic effects of microplastics and nanoplastics
toward zebrafish (Danio rerio) larvae locomotor activity. Results showed that microplastics …

Zebrafish larvae show a clear and distinct pattern of swimming in response to light and dark
conditions, following the development of a swim bladder at 4 days post fertilization. This …

The zebrafish has become a prominent vertebrate model for disease and has already
contributed to several examples of successful phenotype-based drug discovery. For the …

As manufacturing processes and development of new synthetic compounds increase to
keep pace with the expanding global demand, environmental health, and the effects of …

To discover new molecules or review the biological activity and toxicity of therapeutic
substances, drug development, and research relies on robust biological systems to obtain …

Zebrafish (Danio rerio) are a small‐bodied tropical, freshwater fish species originally from
South Asia. The ease of care, year‐round prolific breeding, and transparent, external …