The WHO global influenza surveillance and response system (GISRS)—a future perspective

AJ Hay, JW McCauley - Influenza and other respiratory viruses, 2018 - Wiley Online Library
In the centenary year of the devastating 1918‐19 pandemic, it seems opportune to reflect on
the success of the WHO Global Influenza Surveillance and Response System (GISRS) …

Predictive modeling of influenza shows the promise of applied evolutionary biology

DH Morris, KM Gostic, S Pompei, T Bedford… - Trends in …, 2018 - cell.com
Seasonal influenza is controlled through vaccination campaigns. Evolution of influenza virus
antigens means that vaccines must be updated to match novel strains, and vaccine …

Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants

JM Lee, J Huddleston, MB Doud… - Proceedings of the …, 2018 - National Acad Sciences
Human influenza virus rapidly accumulates mutations in its major surface protein
hemagglutinin (HA). The evolutionary success of influenza virus lineages depends on how …

[HTML][HTML] An atlas of continuous adaptive evolution in endemic human viruses

KE Kistler, T Bedford - Cell host & microbe, 2023 - cell.com
Through antigenic evolution, viruses such as seasonal influenza evade recognition by
neutralizing antibodies. This means that a person with antibodies well tuned to an initial …

Foot and mouth disease vaccine strain selection: current approaches and future perspectives

M Mahapatra, S Parida - Expert review of vaccines, 2018 - Taylor & Francis
Introduction: Lack of cross protection between foot and mouth disease (FMD) virus (FMDV)
serotypes as well as incomplete protection between some subtypes of FMDV affect the …

A biophysical model of viral escape from polyclonal antibodies

TC Yu, ZT Thornton, WW Hannon, WS DeWitt… - Virus …, 2022 - academic.oup.com
A challenge in studying viral immune escape is determining how mutations combine to
escape polyclonal antibodies, which can potentially target multiple distinct viral epitopes …

[HTML][HTML] The inhibition of H1N1 influenza virus-induced apoptosis by silver nanoparticles functionalized with zanamivir

Z Lin, Y Li, M Guo, T Xu, C Wang, M Zhao, H Wang… - RSC …, 2017 - pubs.rsc.org
As one of the most effective drugs for influenza virus infection, clinical application of
zanamivir is restricted with the emergence of resistant influenza virus. It is crucial to …

[HTML][HTML] Understanding dengue virus evolution to support epidemic surveillance and counter-measure development

S Pollett, MC Melendrez, IM Berry, S Duchêne… - Infection, Genetics and …, 2018 - Elsevier
Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global
burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological …

[HTML][HTML] Antigenic characterization of influenza and SARS-CoV-2 viruses

Y Wang, CY Tang, XF Wan - Analytical and Bioanalytical Chemistry, 2022 - Springer
Antigenic characterization of emerging and re-emerging viruses is necessary for the
prevention of and response to outbreaks, evaluation of infection mechanisms …

[HTML][HTML] Estimating the protection afforded by foot-and-mouth disease vaccines in the laboratory

DJ Paton, R Reeve, AV Capozzo, A Ludi - Vaccine, 2019 - Elsevier
Foot-and-mouth disease (FMD) vaccines must be carefully selected and their application
closely monitored to optimise their effectiveness. This review covers serological techniques …