The changing epidemiology of invasive fungal infections

DA Enoch, H Yang, SH Aliyu, C Micallef - Human fungal pathogen …, 2017 - Springer
Invasive fungal infections (IFI) are an emerging problem worldwide with invasive candidiasis
and candidemia responsible for the majority of cases. This is predominantly driven by the …

Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

GC de Oliveira Santos, CC Vasconcelos… - Frontiers in …, 2018 - frontiersin.org
The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …

Incidence, characteristics and outcome of ICU-acquired candidemia in India

A Chakrabarti, P Sood, SM Rudramurthy, S Chen… - Intensive care …, 2015 - Springer
Purpose A systematic epidemiological study on intensive care unit (ICU)-acquired
candidemia across India. Method A prospective, nationwide, multicentric, observational …

Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project

M Bassetti, DR Giacobbe, A Vena, C Trucchi, F Ansaldi… - Critical Care, 2019 - Springer
Background The objective of this study was to assess the cumulative incidence of invasive
candidiasis (IC) in intensive care units (ICUs) in Europe. Methods A multinational …

Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota

S Höfs, S Mogavero, B Hube - Journal of microbiology, 2016 - Springer
The interaction between Candida albicans and its host cells is characterized by a complex
interplay between the expression of fungal virulence factors, which results in adherence …

Invasive candidiasis as a cause of sepsis in the critically ill patient

J Delaloye, T Calandra - Virulence, 2014 - Taylor & Francis
Invasive fungal infections are an increasingly frequent etiology of sepsis in critically ill
patients causing substantial morbidity and mortality. Candida species are by far the …

[HTML][HTML] Current antifungal drugs and immunotherapeutic approaches as promising strategies to treatment of fungal diseases

S Nami, A Aghebati-Maleki, H Morovati… - Biomedicine & …, 2019 - Elsevier
Invasive candidiasis (IC) can affect individuals with various underlying diseases hospitalized
in different parts of hospitals. In recent decades, IC has caused 27–55% mortality in general …

A multicenter study of septic shock due to candidemia: outcomes and predictors of mortality

M Bassetti, E Righi, F Ansaldi, M Merelli, T Cecilia… - Intensive care …, 2014 - Springer
Purpose Candida is the most common cause of severe yeast infections worldwide,
especially in critically ill patients. In this setting, septic shock attributable to Candida is …

[HTML][HTML] Relative frequency of albicans and the various non-albicans Candida spp among candidemia isolates from inpatients in various parts of the world: a …

ME Falagas, N Roussos, KZ Vardakas - International Journal of Infectious …, 2010 - Elsevier
BACKGROUND: Candidemia is among the leading causes of nosocomial bloodstream
infections and is associated with significant mortality. Several centers have published data …

Intensive care medicine research agenda on invasive fungal infection in critically ill patients

M Bassetti, J Garnacho-Montero, T Calandra… - Intensive care …, 2017 - Springer
Purpose To describe concisely the current standards of care, major recent advances,
common beliefs that have been contradicted by recent trials, areas of uncertainty, and …