Microneedle patches have received much interest in the last two decades as drug/vaccine
delivery or fluid sampling systems for diagnostic and monitoring purposes. Microneedles are …

Conventional needle technologies can be advanced with emerging nano-and micro-
fabrication methods to fabricate microneedles. Nano-/micro-fabricated microneedles seek to …

Microneedle arrays provide an efficient tool for transdermal drug delivery in a minimally
invasive and painless manner, showing great potential applications in medicine. However, it …

Background Inner ear diagnostics is limited by the inability to atraumatically obtain samples
of inner ear fluid. The round window membrane (RWM) is an attractive portal for accessing …

Transdermal drug delivery is a viable and clinically proven route of administration. This route
specifically requires overcoming the mechanical barrier provided by the Stratum Corneum of …

Objectives The treatment of inner ear disorders remains challenging due to anatomic
barriers intrinsic to the bony labyrinth. The purpose of this review is to highlight recent …

The ongoing search for biodegradable and biocompatible microneedles (MNs) that are
strong enough to penetrate skin barriers, easy to prepare, and can be translated for clinical …

Microneedles (MNs) are considered to be a novel smart injection system that causes
significantly low skin invasion upon puncturing, due to the micron-sized dimensions that …

Microneedles (MNs) are micron-scale needles that are a painless alternative to injections for
delivering drugs through the skin. MNs find applications as biosensing devices and could …

The application of ultrasound microbubbles (USMBs) enhances the permeability of the
round window membrane (RWM) and improves drug delivery to the inner ear. In this study …