Mechanisms of Intestinal Pharmacokinetic Natural Product-drug Interactions

VO Oyanna, JD Clarke - Drug Metabolism Reviews, 2024 - Taylor & Francis
The growing co-consumption of botanical natural products with conventional medications
has intensified the need to understand potentialeffects on drug safety and efficacy. This …

Lipase-sensitive fusidic acid polymeric nanoparticles based hydrogel for on-demand delivery against MRSA-infected burn wounds

N Ullah, D Khan, N Ahmed, A Zafar, KU Shah… - Journal of Drug Delivery …, 2023 - Elsevier
The present study aimed to develop lipase-sensitive nanoparticles-based hydrogel for
topical delivery of fusidic acid (FA) against wound infection. Lipase sensitive nanosystem for …

Curcumin nanoparticles as a natural antioxidant and antimicrobial preservative against foodborne pathogens in processed chicken fingers

MK Morsy, SY Al-Dalain, MA Haddad… - … in Sustainable Food …, 2023 - frontiersin.org
Introduction Curcumin has highly antimicrobial and antioxidant activities but has poor
bioavailability and low solubility in water. The current study aimed to assess curcumin …

Preparation and in vitro evaluation of controlled-release matrices of losartan potassium using ethocel grade 10 and carbopol 934P NF as rate-controlling polymers

KA Khan, C Zizzadoro, A Di Cerbo, N Pugliese… - Polymers, 2022 - mdpi.com
Controlled-release formulations are essential for those drugs that require fine tuning of their
activity to increase the ratio between therapeutic vs. adverse effects. Losartan potassium is …

Triple-combination therapy for cutaneous leishmaniasis using detergent-free, hyaluronate-coated elastic nanovesicles

K Iqbal, S Khalid, CA McElroy, M Adnan, GM Khan… - …, 2022 - Taylor & Francis
Aim: To develop and evaluate detergent-free, triple-drug-loaded, hyaluronate-coated elastic
nanovesicles (H-ENVs) for the topical treatment of cutaneous leishmaniasis. Materials & …

Formulation and characterization of amiodarone-methyl-beta-cyclodextrin inclusion complexes: A molecular modelling perspective

AM Rubim, JB Rubenick, LO Vendrame… - Journal of Molecular …, 2024 - Elsevier
This study aimed to develop immediate-release tablets containing amiodarone
hydrochloride (AM). AM is a BCS class II compound, ie, high permeable, and poorly soluble …

Molecular Architecture, Computational Exploration and Synthesis of PCL-PEG-PCL Triblock Copolymer-Based Reverse Nanomicelles: A Promising Method for …

D Khan, N Ahmed, M Qindeel, M Mir, N Ullah… - BioNanoScience, 2024 - Springer
Macromolecules such as DNA and proteins play a significant role in the arsenal of
therapeutic molecules. However, site-specific delivery of these materials at the desired rate …

Fabrication of bergenin nanoparticles based hydrogel against infected wounds: An In vitro and In vivo study

A Zafar, D Khan, A ur Rehman, N Ullah… - Journal of Drug Delivery …, 2023 - Elsevier
The present study was aimed to fabricate bergenin polymeric nanoparticles based hydrogel
and to evaluate its therapeutic effectiveness against infected wounds. Polymeric …

Comparative evaluation on the effect of different cavity disinfectant nano gels; Chlorohexidine, Propolis, Liquorice versus Diode Laser in terms of composite …

MM ElMansy, SST Tadros, RS Saleh, R Abdelmonem… - BDJ open, 2023 - nature.com
Introduction The application of different cavity disinfectants is an essential step that
eliminates bacteria after cavity preparation. However, some of these materials may affect …

A Recent Review on Nanocrystal Manufacturing Techniques with Pharmaceutical Application

PS Rathod, MR Narkhede… - … Formerly: Recent Patents …, 2024 - ingentaconnect.com
This review article constitutes an introductory report on nanotechnology focusing on the
various manufacturing approaches of nanocrystals. Nanocrystals are a solid form to tackle …