[HTML][HTML] Regulation of connexin biosynthesis, assembly, gap junction formation, and removal
D Segretain, MM Falk - Biochimica et Biophysica Acta (BBA) …, 2004 - Elsevier
Gap junctions (GJs) are the only known cellular structures that allow a direct transfer of
signaling molecules from cell-to-cell by forming hydrophilic channels that bridge the …
signaling molecules from cell-to-cell by forming hydrophilic channels that bridge the …
Oxidative stress, lens gap junctions, and cataracts
VM Berthoud, EC Beyer - Antioxidants & redox signaling, 2009 - liebertpub.com
The eye lens is constantly subjected to oxidative stress from radiation and other sources.
The lens has several mechanisms to protect its components from oxidative stress and to …
The lens has several mechanisms to protect its components from oxidative stress and to …
[HTML][HTML] Structural organization of gap junction channels
GE Sosinsky, BJ Nicholson - Biochimica et Biophysica Acta (BBA) …, 2005 - Elsevier
Gap junctions were initially described morphologically, and identified as semi-crystalline
arrays of channels linking two cells. This suggested that they may represent an amenable …
arrays of channels linking two cells. This suggested that they may represent an amenable …
The significance of autoantibodies to DFS70/LEDGFp75 in health and disease: integrating basic science with clinical understanding
RL Ochs, M Mahler, A Basu, L Rios-Colon… - Clinical and …, 2016 - Springer
Antinuclear autoantibodies (ANAs) displaying the nuclear dense fine speckled
immunofluorescence (DFS-IIF) pattern in HEp-2 substrates are commonly observed in …
immunofluorescence (DFS-IIF) pattern in HEp-2 substrates are commonly observed in …
Akt phosphorylates Connexin43 on Ser373, a “mode-1” binding site for 14-3-3
DJ Park, CJ Wallick, KD Martyn, AF Lau… - Cell communication & …, 2007 - Taylor & Francis
Connexin43 (Cx43) is a membrane-spanning protein that forms channels that bridge the
gap between adjacent cells and this allows for the intercellular exchange of information …
gap between adjacent cells and this allows for the intercellular exchange of information …
Oxidative activation of protein kinase Cγ through the C1 domain: Effects on gap junctions
D Lin, DJ Takemoto - Journal of Biological Chemistry, 2005 - ASBMB
The accumulation of reactive oxygen species (ROS, for example H 2 O 2) is linked to several
chronic pathologies, including cancer and cardiovascular and neurodegenerative diseases …
chronic pathologies, including cancer and cardiovascular and neurodegenerative diseases …
Autoantigenicity of DFS70 is restricted to the conformational epitope of C-terminal alpha-helical domain
Y Ogawa, K Sugiura, A Watanabe, M Kunimatsu… - Journal of …, 2004 - Elsevier
Autoantibodies against DFS70 (Dense Fine Speckles 70) are found in 30% of Japanese
atopic dermatitis patients, and less frequently in patients with other diseases. We have …
atopic dermatitis patients, and less frequently in patients with other diseases. We have …
Gonadotropin-regulated lymphangiogenesis in ovarian cancer is mediated by LEDGF-induced expression of VEGF-C
S Sapoznik, B Cohen, Y Tzuman, G Meir, S Ben-Dor… - Cancer research, 2009 - AACR
The risk and severity of ovarian carcinoma, the leading cause of gynecologic malignancy
death, are significantly elevated in postmenopausal women. Ovarian failure at menopause …
death, are significantly elevated in postmenopausal women. Ovarian failure at menopause …
[HTML][HTML] Roles and regulation of lens epithelial cell connexins
VM Berthoud, PJ Minogue, P Osmolak, JI Snabb… - FEBS letters, 2014 - Elsevier
The avascular lens of the eye is covered anteriorly by an epithelium containing nucleated,
metabolically active cells. This epithelium contains the first lens cells to encounter noxious …
metabolically active cells. This epithelium contains the first lens cells to encounter noxious …
Transcriptional regulation of vascular endothelial growth factor C by oxidative and thermal stress is mediated by lens epithelium-derived growth factor/p75
B Cohen, Y Addadi, S Sapoznik, G Meir, V Kalchenko… - Neoplasia, 2009 - Elsevier
Vascular endothelial growth factor C (VEGF-C) plays a critical role in tumor
lymphangiogenesis and lymph node metastasis. We report here that VEGF-C expression is …
lymphangiogenesis and lymph node metastasis. We report here that VEGF-C expression is …