Macrophage-derived extracellular vesicles: diverse mediators of pathology and therapeutics in multiple diseases
Y Wang, M Zhao, S Liu, J Guo, Y Lu, J Cheng… - Cell death & …, 2020 - nature.com
Macrophages (Mφ) are primary innate immune cells that exhibit diverse functions in
response to different pathogens or stimuli, and they are extensively involved in the …
response to different pathogens or stimuli, and they are extensively involved in the …
Extracellular vesicles in fungi: past, present, and future perspectives
Extracellular vesicles (EVs) have garnered much interest in the cell biology and biomedical
research fields. Many studies have reported the existence of EVs in all types of living cells …
research fields. Many studies have reported the existence of EVs in all types of living cells …
[HTML][HTML] Exosomes from M1-polarized macrophages enhance paclitaxel antitumor activity by activating macrophages-mediated inflammation
P Wang, H Wang, Q Huang, C Peng, L Yao, H Chen… - Theranostics, 2019 - ncbi.nlm.nih.gov
Objective: Exosomes (Exos) are membrane-encased vesicles derived by nearly all cell types
for intercellular communication and regulation. They also received attention for their use as …
for intercellular communication and regulation. They also received attention for their use as …
Inflammation leads to distinct populations of extracellular vesicles from microglia
Y Yang, A Boza-Serrano, CJR Dunning… - Journal of …, 2018 - Springer
Background Activated microglia play an essential role in inflammatory responses elicited in
the central nervous system (CNS). Microglia-derived extracellular vesicles (EVs) are …
the central nervous system (CNS). Microglia-derived extracellular vesicles (EVs) are …
New Insights in Candida albicans Innate Immunity at the Mucosa: Toxins, Epithelium, Metabolism, and Beyond
A Pellon, SD Sadeghi Nasab… - Frontiers in cellular and …, 2020 - frontiersin.org
The mucosal surfaces of the human body are challenged by millions of microbes on a daily
basis. Co-evolution with these microbes has led to the development of plastic mechanisms …
basis. Co-evolution with these microbes has led to the development of plastic mechanisms …
The IL4I1 enzyme: a new player in the immunosuppressive tumor microenvironment
The high metabolic needs of T lymphocytes in response to activation make them particularly
vulnerable to modifications of their biochemical milieu. Immunosuppressive enzymes …
vulnerable to modifications of their biochemical milieu. Immunosuppressive enzymes …
Candida albicans induces cross-kingdom miRNA trafficking in human monocytes to promote fungal growth
LD Halder, S Babych, DI Palme… - MBio, 2022 - Am Soc Microbiol
In response to infections, human immune cells release extracellular vesicles (EVs) that carry
a situationally adapted cocktail of proteins and nucleic acids, including microRNAs …
a situationally adapted cocktail of proteins and nucleic acids, including microRNAs …
Candida albicans hyphal extracellular vesicles are different from yeast ones, carrying an active proteasome complex and showing a different role in host immune …
R Martínez-López, ML Hernáez, E Redondo… - Microbiology …, 2022 - Am Soc Microbiol
Candida albicans is the principal causative agent of lethal fungal infections, predominantly
in immunocompromised hosts. Extracellular vesicles (EVs) have been described as crucial …
in immunocompromised hosts. Extracellular vesicles (EVs) have been described as crucial …
Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles
JV Santiago, A Natu, CC Ramelow, S Rayaprolu… - Molecular & Cellular …, 2023 - ASBMB
Microglia are resident immune cells of the brain that play important roles in mediating
inflammatory responses in several neurological diseases via direct and indirect …
inflammatory responses in several neurological diseases via direct and indirect …
Immune modulation by complement receptor 3-dependent human monocyte TGF-β1-transporting vesicles
Extracellular vesicles have an important function in cellular communication. Here, we show
that human and mouse monocytes release TGF-β1-transporting vesicles in response to the …
that human and mouse monocytes release TGF-β1-transporting vesicles in response to the …