[HTML][HTML] Ginsenosides in Panax genus and their biosynthesis
M Hou, R Wang, S Zhao, Z Wang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Ginsenosides are a series of glycosylated triterpenoids which belong to protopanaxadiol
(PPD)-, protopanaxatriol (PPT)-, ocotillol (OCT)-and oleanane (OA)-type saponins known as …
(PPD)-, protopanaxatriol (PPT)-, ocotillol (OCT)-and oleanane (OA)-type saponins known as …
Recent advances in triterpenoid pathway elucidation and engineering
Triterpenoids are among the most assorted class of specialized metabolites found in all the
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …
Characterization of the horse chestnut genome reveals the evolution of aescin and aesculin biosynthesis
W Sun, Q Yin, H Wan, R Gao, C Xiong, C Xie… - Nature …, 2023 - nature.com
Horse chestnut (Aesculus chinensis) is an important medicinal tree that contains various
bioactive compounds, such as aescin, barrigenol-type triterpenoid saponins (BAT), and …
bioactive compounds, such as aescin, barrigenol-type triterpenoid saponins (BAT), and …
Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants
Diosgenin is a spiroketal steroidal natural product extracted from plants and used as the
single most important precursor for the world steroid hormone industry. The sporadic …
single most important precursor for the world steroid hormone industry. The sporadic …
A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis
SY Chung, H Seki, Y Fujisawa, Y Shimoda… - Nature …, 2020 - nature.com
Triterpenoid saponins are specialised metabolites distributed widely in the plant kingdom
that consist of one or more sugar moieties attached to triterpenoid aglycones. Despite the …
that consist of one or more sugar moieties attached to triterpenoid aglycones. Despite the …
Triterpenoid-biosynthetic UDP-glycosyltransferases from plants
Triterpenoid saponins are naturally occurring structurally diverse glycosides of triterpenes
that are widely distributed among plant species. Great interest has been expressed by …
that are widely distributed among plant species. Great interest has been expressed by …
Plant triterpenoid saponins: biosynthesis, in vitro production, and pharmacological relevance
T Biswas, UN Dwivedi - Protoplasma, 2019 - Springer
The saponins are a diverse class of natural products, with a broad scale distribution across
different plant species. Chemically characterized as triterpenoid glycosides, they posses a …
different plant species. Chemically characterized as triterpenoid glycosides, they posses a …
[HTML][HTML] A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules
J Reed, MJ Stephenson, K Miettinen, B Brouwer… - Metabolic …, 2017 - Elsevier
Plants are an excellent source of drug leads. However availability is limited by access to
source species, low abundance and recalcitrance to chemical synthesis. Although plant …
source species, low abundance and recalcitrance to chemical synthesis. Although plant …
[HTML][HTML] Synergistic mechanisms of constituents in herbal extracts during intestinal absorption: Focus on natural occurring nanoparticles
The systematic separation strategy has long and widely been applied in the research and
development of herbal medicines. However, the pharmacological effects of many bioactive …
development of herbal medicines. However, the pharmacological effects of many bioactive …
Draft genome assembly and annotation of Glycyrrhiza uralensis, a medicinal legume
K Mochida, T Sakurai, H Seki, T Yoshida… - The Plant …, 2017 - Wiley Online Library
Chinese liquorice/licorice (Glycyrrhiza uralensis) is a leguminous plant species whose roots
and rhizomes have been widely used as a herbal medicine and natural sweetener. Whole …
and rhizomes have been widely used as a herbal medicine and natural sweetener. Whole …