Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with a
considerable socioeconomic burden. Heterogeneity of pathoanatomical subtypes and …

Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …

The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …

Alzheimer's disease (AD) is caused by a complex interaction between genetic and
environmental factors. However, how the role of peripheral organ changes in response to …

Traditionally seen as a sudden, brutal event with short-term impairment, traumatic brain
injury (TBI) may cause persistent, sometimes life-long, consequences. While mortality after …

The most common forms of acquired epilepsies arise following acute brain insults such as
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …

Within minutes of a traumatic impact, a robust inflammatory response is elicited in the injured
brain. The complexity of this post-traumatic squeal involves a cellular component …

Background The neuroinflammatory response following traumatic brain injury (TBI) is known
to be a key secondary injury factor that can drive ongoing neuronal injury. Despite this …

Over the past two decades it became evident that the immune system plays a central role in
modulating learning, memory and neural plasticity. Under normal quiescent conditions …