T cell dynamics with neoadjuvant immunotherapy in head and neck cancer

M Zhao, JD Schoenfeld, AM Egloff, GJ Hanna… - Nature Reviews …, 2024 - nature.com
Immune-checkpoint inhibitors (ICIs) are being tested as neoadjuvant therapies in various
solid tumours, including in patients with head and neck squamous cell carcinoma (HNSCC) …

The Use of Contrast-Enhanced Sonography for Therapy Monitoring of Metastatic Lymph Nodes: A Systematic Review

M Rink, EM Jung, J Kuenzel - Current Oncology, 2023 - mdpi.com
Metastatic cervical lymph nodes are a frequent finding in head and neck squamous cell
carcinoma (HNSCC). If a non-surgical approach is primarily chosen, a therapy response …

Novel vaccination strategies based on optimal stimulation of CD4+ T helper cells for the treatment of oral squamous cell carcinoma

L Azzi, F Celesti, AM Chiaravalli, AKB Shaik… - Frontiers in …, 2024 - frontiersin.org
Oral Squamous Cell Carcinoma (OSCC) is the most common malignant tumor of the oral
cavity. Despite recent advances in the field of oral cancer therapy, including the introduction …

[HTML][HTML] Prediction of Oral Cancer Biomarkers by Salivary Proteomics Data

V Remori, M Airoldi, T Alberio, M Fasano… - International Journal of …, 2024 - mdpi.com
Oral cancer, representing 2–4% of all cancer cases, predominantly consists of Oral
Squamous Cell Carcinoma (OSCC), which makes up 90% of oral malignancies. Early …

Neoadjuvant therapy with chemotherapy and immune checkpoint inhibitor for laryngeal function preservation in locally advanced hypopharyngeal cancer

SG Wu, RJ Wang, Y Zhou, XY Luo - Frontiers in Immunology, 2024 - frontiersin.org
Purpose To evaluate the efficacy and laryngeal function preservation of neoadjuvant
treatment with chemotherapy and immune checkpoint inhibitor for locally advanced …

[HTML][HTML] Evaluation of neck control strategies for oral squamous cell carcinoma of stage I: Neck dissection or potential immunotherapy

C Yang, Z Wang, L Shi, W Liu - Journal of Dental Sciences, 2024 - Elsevier
The neck control strategies of early-stage oral squamous cell carcinoma (OSCC) patients
with clinical node-negative neck remain uncertain. These patients could be benefit from …

Protein Translation Dysregulation and Immune Cell Evasion Define Metastatic Clones in HPV-related Cancer of the Oropharynx

V Chin, W Muskovic, RA McCloy, D Neavin, J Alquicira… - bioRxiv, 2024 - biorxiv.org
Head and neck cancers, representing the seventh most common malignancy globally, have
seen a shift in causative factors from traditional smoking and alcohol use to human …

Whether early-stage (N0 neck) oral cancer patients received primary tumor resection without neck dissection benefit from immune checkpoint therapy

W Liu, X Shen, L Shi, Y He - International Journal of Surgery, 2023 - journals.lww.com
Oral squamous cell carcinoma (OSCC), representing more than 90% of oral cavity cancer, is
characterized by a high risk of neck regional lymph node (LN) metastasis, especially the …

[HTML][HTML] Neoadjuvant pembrolizumab-carboplatin-paclitaxel in locally advanced squamous cell carcinoma of the oral cavity: A case report and literature review

A Hesham, F AlOtaibi, DD Kim, Y Alshamrani… - Oral Oncology …, 2024 - Elsevier
Head and neck cancers are being diagnosed more frequently in elderly patients and at
advanced stages. In these cases, standard treatment methods are often not feasible due to …

Spezielle Tumorentitäten im Kopf-Hals-Bereich: Karzinome von Nasopharynx, Speicheldrüsen, Nasenhaupt/-nebenhöhlen und Schilddrüse

HB Zech, CS Betz - HNO, 2024 - Springer
Zusammenfassung Hintergrund Tumoren des Nasopharynx (NPC), der Nasenhaupt-und
nebenhöhlen, der Speicheldrüsen und der Schilddrüse (SD-CA) sind gegenüber Kopf-Hals …