The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy
have been assessed in several clinical trials. These trials can be categorized as those using …

Background—Despite rapid clinical translation and widespread enthusiasm, the therapeutic
benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart …

Background A promising approach to the treatment of chronic ischaemic heart disease and
congestive heart failure is the use of stem cells. The last decade has seen a plethora of …

Abstract The Third Universal Definition of Myocardial Infarction (MI) requires cardiac
myocyte necrosis with an increase and/or a decrease in a patient's plasma of cardiac …

Therapeutic angiogenesis may improve outcomes in patients with coronary artery disease
undergoing surgical revascularization. Angiogenic factors may promote blood vessel growth …

Background The results from small clinical studies suggest that therapy with adult bone
marrow (BM)–derived cells (BMCs) reduces infarct size and improves left ventricular function …

Context Stem cell therapy is rapidly developing and has generated excitement and promise
as well as confusion and at times contradictory results in the lay and scientific literature …

Accumulating laboratory studies have implicated the mobilization of bone marrow (BM)-
derived stem cells in brain plasticity and stroke therapy. This mobilization of bone cells to the …

Historically, revascularization of ischemic tissue was believed to occur through the migration
and proliferation of endothelial cells in nearby tissues; however, evidence accumulated in …

Introduction Stem cell therapy has emerged as a promising strategy for the treatment of
ischemic cardiomyopathy. Sources of data Multiple candidate cell types have been used in …