The knee is the joint most frequently involved in osteoarthritis and represents a significant
contributor to patient morbidity and impaired functional status. Major risk factors include …

White adipose tissue (WAT) is a specialized tissue whose main function is lipid synthesis
and triglyceride storage. It is now considered as an active organ secreting a plethora of …

Abstract Purpose of Review Metabolic syndrome (MetS), also called the 'deadly
quartet'comprising obesity, diabetes, dyslipidemia, and hypertension, has been ascertained …

Osteoarthritis (OA) is a complex disease of whole joints with progressive cartilage matrix
degradation and chondrocyte transformation. The inflammatory features of OA are reflected …

Aging is a physical procedure for people and nature. Our aging world is expanding because
of the life span extension. Aging has a crucial relationship with our body composition …

Adipokines are the principal mediators in adipose signaling. Nevertheless, besides their role
in energy storage, these molecules can be produced by other cells, such as immune cells or …

Osteoarthritis (OA) is a whole-joint disease that affects cartilage, bone, and synovium as well
as ligaments, menisci, and muscles. Although previously considered to be a …

This study examined the effects of obesity on cartilage mechanics and longitudinal failure
probability at the medial tibiofemoral compartment, using combined musculoskeletal …

Adipokines are a heterogeneous group of signalling molecules secreted prevalently by
adipose tissue. Initially considered as regulators of energy metabolism and appetite …

Bone is a dynamic tissue reshaped by constant bone formation and bone resorption to
maintain its function. The skeletal system accounts for approximately 70% of the total volume …