Many cells use the cell membrane potential to regulate their physiologic functions. Among
the better known examples are:(1) regulation of sodium and potassium permeabilities in …

The concept of excitation–contraction coupling is almost as old as Journal of General
Physiology. It was understood as early as the 1940s that a series of stereotyped events is …

The structure of the junction between sarcoplasmic reticulum (SR) and transverse tubular (T)
system at the triad has been studied in twitch fibers of the frog. The junction is formed by …

The sarcoplasmic reticulum (SR) and transverse tubular system (TTS) of a fast-twitch muscle
(extensor digitorum longus-EDL) and a slow-twitch muscle (soleus-SOL) of the mouse were …

This book offers a comparative and interdisciplinary approach to excitation-contraction-
coupling in smooth and striated mus cles, including the myocardium. It is an account of the …

1. Voltage‐clamp experiments were carried out using the techniques described in the
preceding paper. 2. In one series of experiments an attempt was made to disrupt the T …

A quantitative analysis of the volumes, surface areas, and dimensions of the ultrastructural
components in the soleus muscle fibers of the guinea pig was made by using point counting …

Ions in water are the liquid of life. Life occurs almost entirely in “salt water.” Life began in
salty oceans. Animals kept that salt water within them when they moved out of the ocean to …

1. The excitatory process travelling along the T‐system may be either electrotonic or
regenerative. If Na+ dependent action potential is present in the tubular membranes, high …

An improved immunogold labeling procedure was used to examine the subcellular
distribution of glucose transporters in Lowricryl HM20-embedded skeletal muscle from …