The impact of adult neurogenesis on affective functions: of mice and men

M Alonso, AC Petit, PM Lledo - Molecular Psychiatry, 2024 - nature.com
In most mammals, new neurons are not only produced during embryogenesis but also after
birth. Soon after adult neurogenesis was discovered, the influence of recruiting new neurons …

Ageing, cognitive decline, and effects of physical exercise: complexities, and considerations from animal models

GM Caruso, S Nicolas, PJ Lucassen, JD Mul… - Brain …, 2024 - content.iospress.com
In our ageing global population, the cognitive decline associated with dementia and
neurodegenerative diseases represents a major healthcare problem. To date, there are no …

[HTML][HTML] Memory Circuits in Dementia: The Engram, Hippocampal Neurogenesis and Alzheimer's disease

O Lazarov, M Gupta, P Kumar, Z Morrissey… - Progress in …, 2024 - Elsevier
Here, we provide an in-depth consideration of our current understanding of engrams,
spanning from molecular to network levels, and hippocampal neurogenesis, in health and …

Adult neurogenesis, context encoding, and pattern separation: A pathway for treating overgeneralization

W Chang, R Hen - Engrams: A Window into the Memory Trace, 2024 - Springer
In mammals, the subgranular zone of the dentate gyrus is one of two brain regions (with the
subventricular zone of the olfactory bulb) that continues to generate new neurons throughout …

Stem cell expression of CXCR4 regulates tissue composition in the vomeronasal organ

A Dietz, K Senf, EM Neuhaus - Journal of Cell Science, 2025 - journals.biologists.com
The vomeronasal organ (VNO) detects signaling molecules that often prompt innate
behaviors, such as aggression and reproduction. Vomeronasal sensory neurons, classified …

A roadmap to human hippocampal neurogenesis in adulthood, aging and AD.

O Lazarov, A Disouky, M Sanborn, M Mostafa… - 2024 - researchsquare.com
In the rodent, hippocampal neurogenesis plays critical roles in learning and memory 1, 2, is
tightly regulated by inhibitory neurons 3-7 and contributes to memory dysfunction in …

[PDF][PDF] Systems Medicine for the Molecular Characterization of Alzheimer's Disease and the Drug Repurposing Strategy

A Bayraktar, A Mardinoglu, S Shoaie - 2023 - kclpure.kcl.ac.uk
Alzheimer's disease (AD) is a complex multifactorial brain disorder characterised by
dementia, neurodegeneration, plaques and neurofibrillary tangles in elderly people. The …

[PDF][PDF] FORMALİNLE FİKSE EDİLMİŞ PARAFİNE GÖMÜLÜ DOKULARDA İKİ FARKLI HIZLI DOKU ŞEFFAFLANDIRMA YÖNTEMİNİN ETKİNLİĞİNİN …

GG ALVER - apbseski.mersin.edu.tr
Standart histolojik yöntemlerle hazırlanan ve sıklıkla parafine gömülü olan dokulardan elde
edilen kesitler ile doku veya hücre yapıları hakkında iki boyutlu görüntüler elde …