The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Oral Cavity and Candida albicans: Colonisation to the Development of Infection

M Patel - Pathogens, 2022 - mdpi.com
Candida colonisation of the oral cavity increases in immunocompromised individuals which
leads to the development of oral candidiasis. In addition, host factors such as xerostomia …

Candida albicans pathogenicity mechanisms

FL Mayer, D Wilson, B Hube - Virulence, 2013 - Taylor & Francis
The polymorphic fungus Candida albicans is a member of the normal human microbiome. In
most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain …

Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota

S Höfs, S Mogavero, B Hube - Journal of microbiology, 2016 - Springer
The interaction between Candida albicans and its host cells is characterized by a complex
interplay between the expression of fungal virulence factors, which results in adherence …

Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review

N Kalia, J Singh, M Kaur - Annals of clinical microbiology and …, 2020 - Springer
Recurrent vulvovaginal infections (RVVI) has not only become an epidemiological and
clinical problem but also include large social and psychological consequences …

Mechanism of Candida pathogenesis: revisiting the vital drivers

IE Mba, EI Nweze - European Journal of Clinical Microbiology & Infectious …, 2020 - Springer
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …

Candida albicans Als3, a multifunctional adhesin and invasin

Y Liu, SG Filler - Eukaryotic cell, 2011 - Am Soc Microbiol
Candida albicans is part of the normal human flora, and it grows on mucosal surfaces in
healthy individuals. In susceptible hosts, this organism can cause both mucosal and …

[HTML][HTML] Candida albicans interactions with epithelial cells and mucosal immunity

JR Naglik, DL Moyes, B Wächtler, B Hube - Microbes and infection, 2011 - Elsevier
Candida albicans interactions with epithelial cells are critical for commensal growth, fungal
pathogenicity and host defence. This review will outline our current understanding of C …

Mechanisms of fungal dissemination

AB Strickland, M Shi - Cellular and Molecular Life Sciences, 2021 - Springer
Fungal infections are an increasing threat to global public health. There are more than six
million fungal species worldwide, but less than 1% are known to infect humans. Most of …

Candida albicans-Epithelial Interactions: Dissecting the Roles of Active Penetration, Induced Endocytosis and Host Factors on the Infection Process

B Wächtler, F Citiulo, N Jablonowski, S Förster, F Dalle… - PloS one, 2012 - journals.plos.org
Candida albicans frequently causes superficial infections by invading and damaging
epithelial cells, but may also cause systemic infections by penetrating through epithelial …