Hypoglycemia in patient with type 2 diabetes treated with insulin: it can happen

SR Heller, M Peyrot, SK Oates… - BMJ Open Diabetes …, 2020 - drc.bmj.com
There are many misconceptions about the prevalence and effects of hypoglycemia in people
with type 2 diabetes (T2D), including hypoglycemia does not occur or does not have …

Executive function and diabetes: a clinical neuropsychology perspective

Q Zhao, Y Zhang, X Liao, W Wang - Frontiers in Psychology, 2020 - frontiersin.org
Objective Diabetes is a global public health concern. Management of diabetes depends on
successful implementation of strategies to alleviate decline in executive functions (EFs), a …

Low‐glucose‐sensitive TRPC6 dysfunction drives hypoglycemia‐induced cognitive impairment in diabetes

C He, P Gao, Y Cui, Q Li, Y Li, Z Lu… - Clinical and …, 2020 - Wiley Online Library
Background Recurrent moderate hypoglycemia (RH), a major adverse effect of
hypoglycemic therapy in diabetic patients, is one of the main risk factors for cognitive …

Metabolic Profile of Alzheimer's Disease: Is 10-Hydroxy-2-decenoic Acid a Pertinent Metabolic Adjuster?

Y Gong, H Luo, Z Li, Y Feng, Z Liu, J Chang - Metabolites, 2023 - mdpi.com
Alzheimer's disease (AD) represents a significant public health concern in modern society.
Metabolic syndrome (MetS), which includes diabetes mellitus (DM) and obesity, represents …

SIRT3 alleviates mitochondrial dysfunction induced by recurrent low glucose and improves the supportive function of astrocytes to neurons

R Gao, Z Chen, Y Wu, R Chen, W Zheng, L Qi… - Free Radical Biology …, 2022 - Elsevier
Hypoglycemia is an independent risk factor of cognitive impairment in patients with diabetes.
Our previous study indicated that dysfunction of astrocytic mitochondria induced by recurrent …

Recurrent non-severe hypoglycemia aggravates cognitive decline in diabetes and induces mitochondrial dysfunction in cultured astrocytes

R Gao, L Ren, Y Zhou, L Wang, Y Xie, M Zhang… - Molecular and Cellular …, 2021 - Elsevier
The present study aimed to determine the relationship between astrocytes and recurrent non-
severe hypoglycemia (RH) 2-associated cognitive decline in diabetes. RH induced cognitive …

Allo Beta Cell transplantation: specific features, unanswered questions, and immunological challenge

R Caldara, V Tomajer, P Monti, V Sordi, A Citro… - Frontiers in …, 2023 - frontiersin.org
Type 1 diabetes (T1D) presents a persistent medical challenge, demanding innovative
strategies for sustained glycemic control and enhanced patient well-being. Beta cells are …

[HTML][HTML] Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A …

NJ Jensen, HZ Wodschow, MJ Skytte, A Samkani… - Clinical Nutrition, 2022 - Elsevier
Background & aims We evaluated the effect of weight loss induced by dietary carbohydrate
restriction on health-related quality of life (HRQoL) and cognition in type 2 diabetes (T2D) …

Mitigation of rebound hyperglycemia with real-time continuous glucose monitoring data and predictive alerts

G Acciaroli, JB Welsh… - Journal of Diabetes …, 2022 - journals.sagepub.com
Background: Excess carbohydrate intake during hypoglycemia can lead to rebound
hyperglycemia (RH). We investigated associations between RH and use of real-time …

Effects of β-hydroxybutyrate on cognition in patients with type 2 diabetes

NJ Jensen, M Nilsson, JS Ingerslev… - European Journal of …, 2020 - academic.oup.com
Objective Cognitive impairment in type 2 diabetes is associated with cerebral glucose
hypometabolism. Providing a glucose substitute such as ketone bodies might restore …