Oxidative stress and chronic inflammation in osteoarthritis: can NRF2 counteract these partners in crime?

AS Marchev, PA Dimitrova, AJ Burns… - Annals of the New …, 2017 - Wiley Online Library
Osteoarthritis (OA) is an age‐related joint degenerative disease associated with pain, joint
deformity, and disability. The disease starts with cartilage damage but then progressively …

Therapeutic potentials of antiviral plants used in traditional african medicine with COVID-19 in focus: a Nigerian perspective

AF Attah, AA Fagbemi, O Olubiyi… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic is caused by an infectious novel strain
of coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study

A Haroyan, V Mukuchyan, N Mkrtchyan… - … and alternative medicine, 2018 - Springer
Background The aim of this clinical trial was to assess the efficacy and safety of curcuminoid
complex extract from turmeric rhizome with turmeric volatile oil (CuraMed®) and its …

Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study

V Kuptniratsaikul, P Dajpratham… - … Interventions in aging, 2014 - Taylor & Francis
Objective To determine the efficacy and safety of Curcuma domestica extracts in pain
reduction and functional improvement. Methods 367 primary knee osteoarthritis patients with …

[PDF][PDF] Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients

G Belcaro, MR Cesarone, M Dugall, L Pellegrini… - Altern Med …, 2010 - researchgate.net
In a previous three-month study of Meriva®, a proprietary curcumin-phosphatidylcholine
phytosome complex, decreased joint pain and improvement in joint function were observed …

Curcumin Inhibits the PERK‐eIF2α‐CHOP Pathway through Promoting SIRT1 Expression in Oxidative Stress‐induced Rat Chondrocytes and Ameliorates …

K Feng, Y Ge, Z Chen, X Li, Z Liu, X Li… - Oxidative Medicine …, 2019 - Wiley Online Library
Oxidative stress plays a crucial role in the occurrence and development of osteoarthritis (OA)
through the activation of endoplasmic reticulum (ER) stress. Curcumin is a polyphenolic …

Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms in a post-traumatic osteoarthritis mouse model

Z Zhang, DJ Leong, L Xu, Z He, A Wang… - Arthritis research & …, 2016 - Springer
Background Curcumin has been shown to have chondroprotective potential in vitro.
However, its effect on disease and symptom modification in osteoarthritis (OA) is largely …

Curcumin and obesity

PG Bradford - Biofactors, 2013 - Wiley Online Library
Turmeric has been long recognized for its anti‐inflammatory and health‐promoting
properties. Curcumin is one of the principal anti‐inflammatory and healthful components of …

Therapeutic potential of phytoconstituents in management of Alzheimer's disease

AK Singh, SN Rai, A Maurya, G Mishra… - Evidence‐Based …, 2021 - Wiley Online Library
Since primitive times, herbs have been extensively used in conventional remedies for
boosting cognitive impairment and age‐associated memory loss. It is mentioned that …

Anti-inflammatory Effect of Curcuma longa and Allium hookeri Co-treatment via NF-κB and COX-2 Pathways

SY Lee, SS Cho, YC Li, CS Bae, KM Park, DH Park - Scientific reports, 2020 - nature.com
Although inflammation is a host defense mechanism, chronic inflammation mediates several
diseases, including cancer, allergy, asthma, and autoimmune diseases, and reportedly, it is …