Cellular and stromal components including tumor cells, immune cells, mesenchymal cells,
cancer-linked fibroblasts, and extracellular matrix, constituent tumor microenvironment …

Copper is an essential trace element that plays a critical role in a variety of basic biological
functions, and serves as a key component in a number of copper-dependent enzymes that …

Photosensitizer-based photodynamic therapy (PDT) can not only kill tumor cells by the
generated cytotoxic reactive oxygen species (ROS), but also trigger immunogenic cell death …

Avoiding the low specificity of phototheranostic reagents at the tumor site is a major
challenge in cancer phototherapy. Meanwhile, angiogenesis in the tumor is not only the …

Copper ions are needed in several steps of cancer progression. However, the underlying
mechanisms, and involved copper-binding proteins, are mainly elusive. Since most copper …

The microenvironment in which cancer resides plays an important role in regulating cancer
survival, progression, malignancy and drug resistance. Tumor microenvironment (TME) …

Triple‐negative breast cancer (TNBC) is the most aggressive breast cancer subtype and
lacks specific targeted therapeutic agents. The current mechanistic evidence from cell …

Simple Summary Oligometastatic disease is a condition in oncology where cancer affects
only a few distant sites. It is associated with a low-burden spread and a more favorable …

Rationale: Alternative therapeutic strategies based on tumor-specific molecular targets are
urgently needed for triple-negative breast cancer (TNBC). The protease cathepsin D (cath …

Introduction Heavy metals were classified as essential, probably essential, and potentially
toxic in the general population. Until now, it has been reported inconsistently on the …