Molecular and cellular mechanisms of propolis and its polyphenolic compounds against cancer

N Oršolić, M Jazvinšćak Jembrek - International journal of molecular …, 2022 - mdpi.com
In recent years, interest in natural products such as alternative sources of pharmaceuticals
for numerous chronic diseases, including tumors, has been renewed. Propolis, a natural …

Cyclooxygenase-2 inhibitors as a therapeutic target in inflammatory diseases

MD Ferrer, C Busquets-Cortés, X Capó… - Current medicinal …, 2019 - ingentaconnect.com
Inflammation plays a crucial role in the development of many complex diseases and
disorders including autoimmune diseases, metabolic syndrome, neurodegenerative …

Hydroxycinnamic acids and derivatives formulations for skin damages and disorders: A review

M Contardi, M Lenzuni, F Fiorentini, M Summa… - Pharmaceutics, 2021 - mdpi.com
Alterations of skin homeostasis are widely diffused in our everyday life both due to
accidental injuries, such as wounds and burns, and physiological conditions, such as late …

Potential effects of phenolic compounds that can be found in olive oil on wound healing

L Melguizo-Rodríguez, E de Luna-Bertos… - Foods, 2021 - mdpi.com
The treatment of tissue damage produced by physical, chemical, or mechanical agents
involves considerable direct and indirect costs to health care systems. Wound healing …

Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway

W Sun, W Xie, D Huang, Y Cui… - International …, 2022 - spandidos-publications.com
Osteoarthritis (OA) is the most common degenerative disease affecting the joints, and
inflammation appears to play a critical role in the initiation and progression of OA. Caffeic …

Allergic inflammation: Effect of propolis and its flavonoids

N Oršolić - Molecules, 2022 - mdpi.com
The incidence of allergic diseases and their complications are increasing worldwide. Today,
people increasingly use natural products, which has been termed a “return to nature” …

Recent progresses in the pharmacological activities of caffeic acid phenethyl ester

L Lv, H Cui, Z Ma, X Liu, L Yang - Naunyn-Schmiedeberg's Archives of …, 2021 - Springer
The past decades have seen a growing interest in natural products. Caffeic acid phenethyl
ester (CAPE), a flavonoid isolated from honeybee propolis, has shown multiple …

Caffeic acid phenethyl ester attenuates lipopolysaccharide-stimulated proinflammatory responses in human gingival fibroblasts via NF-κB and PI3K/Akt signaling …

L Li, W Sun, T Wu, R Lu, B Shi - European Journal of Pharmacology, 2017 - Elsevier
Periodontal diseases often begin with chronic gingival inflammation, which causes the
destruction of periodontal tissues. Inflammatory immune responses from host cells to …

Caffeic acid phenethyl ester promotes wound healing of mice pressure ulcers affecting NF-κB, NOS2 and NRF2 expression

B Romana-Souza, JS Dos Santos, A Monte-Alto-Costa - Life sciences, 2018 - Elsevier
Aims In pressure ulcers, the synthesis of reactive oxygen species induced by ischemia and
reperfusion leads to chronic inflammation and tissue damage, which impair the closure of …

Lavandula austroapennina (Lamiaceae): Getting Insights into Bioactive Polyphenols of a Rare Italian Endemic Vascular Plant

C Gravina, M Formato, S Piccolella… - International Journal of …, 2023 - mdpi.com
Lavandula austroapennina NG Passal., Tundis and Upon has recently been described as a
new species endemic to the southern Apennines (Italy). Locally, this species has a long …