KRAS, one of the RAS protein family members, plays an important role in autophagy and
apoptosis, through the regulation of several downstream effectors. In cancer cells, KRAS …

Colorectal cancer (CRC) is one of the most common human malignancies worldwide. Along
with apoptosis and inflammation, autophagy is one of three important mechanisms in CRC …

Colorectal cancer (CRC) is among the topmost malignancies for both genders. Despite the
high incidence rate and advances in diagnostic tools, treatment in many cases is still …

Understanding the mechanisms of colorectal cancer progression is crucial in the setting of
strategies for its prevention. δ-Valerobetaine (δVB) is an emerging dietary metabolite …

Simple Summary Autophagy is the capability of cells to dismantle and recycle parts of
themselves. This process is closely intertwined with other crucial cell functions, such as …

Colitis associated colorectal cancer is a disease with a high incidence and complex course
that develops from chronic inflammation and deteriorates after various immune responses …

Neutrophils are abundant immune cells in the colon tumor microenvironment. Studies have
shown that neutrophils are recruited into hypoxic foci in colon cancer. However, the impact …

Colitis-associated colorectal cancer (CACC) is one of the devastating complications of long-
term inflammatory bowel disease and is associated with substantial morbidity and mortality …

Colorectal cancer (CRC) develops and progresses in a nutritional environment comprising a
continuously changing luminal cocktail of external dietary and microbial factors on the apical …

Mitochondria are dynamic organelles that function in cellular energy metabolism,
intracellular and extracellular signalling, cellular fate and stress responses. Mitochondria of …