The development and application of emerging technologies of Industry 4.0 enable the
realization of digital twins (DT), which facilitates the transformation of the manufacturing …

Blend uniformity is a critical quality attribute in continuous pharmaceutical manufacturing.
However, its measurement is challenging due to the difficulty and inaccessibility of sampling …

Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …

Content uniformity (CU) of the active pharmaceutical ingredient is a critical quality attribute of
tablets as a dosage form, ensuring reproducible drug potency. Failure to meet the accepted …

Mathematical modelling of infrared spectra using multivariate statistics is generating
increasingly better results in the determination of molecular properties of substances. In this …

Profiles of Drug Substances, Excipients, and Related Methodology, Volume 47 covers all
aspects of drug development and formulation of drugs, meeting the information needs of the …

This work presents a system, where deep learning was used on images captured with a
digital camera to simultaneously determine the API concentration and the particle size …

Near infrared (NIR) spectroscopy has been widely recognized as a powerful PAT tool for
monitoring blend uniformity in continuous manufacturing (CM) processes. However, the …

This present review described the application of chemometrics using direct spectroscopic
methods at the quality control (QC) laboratory of Pharmaceutical Industries. Using …

Near-infrared spectroscopy (NIRS) is nowadays an established analytical technique in the
pharmaceutical industry. The aim of this review is to present the progress of NIRS in …