The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …

Metallodrugs have a central role in the treatment and diagnosis of diseases. To overcome
potential toxicity and equip metal-based anticancer agents with biological activity, the choice …

Cancer treatments, including traditional chemotherapy, have failed to cure human
malignancies. The main reasons for the failure of these treatments are the inevitable drug …

Four bipyridine-type ligands variably derivatized with two bioactive groups (taken from
ethacrynic acid, flurbiprofen, biotin, and benzylpenicillin) were prepared via sequential …

Glycoconjugation is a powerful tool to improve the anticancer activity of metal complexes.
Herein, we modified commercial arylphosphanes with carbohydrate-derived fragments for …

Ruthenium (Ru) complexes have unfulfilled promise for the treatment of cancers. In the last
two decades, a lot of work has been undertaken to design Ru complexes and understand …

[M (arene)(HQ) Cl] complexes (M= RuII/OsII/RhIII/IrIII; HQ= 8-hydroxyquinoline) have shown
promise as anticancer agents. To assess the effect of conjugating biotin (vitamin B7) to such …

The cytotoxicities of seven dimeric metal species of the general formula [M (arene) Cl2] 2,
commonly used as precursors for complex synthesis and deemed biologically inactive, are …

This chapter covers the literature published during 2020 relating to the synthesis of tertiary
phosphines. Although it has been necessary to continue to be selective in the choice of …

This chapter covers scientific contributions in quinquevalent organo-phosphorus chemistry
published in the literature in 2021. The review is not comprehensive but shows the most …