Current perspectives on the diagnosis and management of healthcare-associated ventriculitis and meningitis

M Karvouniaris, A Brotis, K Tsiakos, E Palli… - Infection and Drug …, 2022 - Taylor & Francis
Ventriculitis or post-neurosurgical meningitis or healthcare-associated ventriculitis and
meningitis (VM) is a severe infection that complicates central nervous system operations or …

Intrathecal or intraventricular antimicrobial therapy for post-neurosurgical Gram-negative bacillary meningitis or ventriculitis: A systematic review and meta-analysis

MT Li, QQ Wu, JB Li, JS Chen - International journal of antimicrobial agents, 2024 - Elsevier
ABSTRACT Purpose Extensively-drug-resistant Gram-negative bacteria (XDR GNB)-related
post-neurosurgical infection is closely related to mortality, which represents a major …

Characterization and diagnosis spectrum of patients with cerebrospinal fluid pleocytosis

S Dyckhoff-Shen, JP Bewersdorf, NC Teske, S Völk… - Infection, 2024 - Springer
Purpose There is an overlap in the cerebrospinal fluid (CSF) characteristics of patients
presenting with different etiologies of CSF pleocytosis. Here, we characterized patients with …

Intelligent clinical lab for the diagnosis of post-neurosurgical meningitis based on machine-learning-aided cerebrospinal fluid analysis

R Xie, X Song, H Chen, P Lin, S Guo… - Analytical …, 2022 - ACS Publications
Post-neurosurgical meningitis (PNM) often leads to serious consequences; unfortunately,
the commonly used clinical diagnostic methods of PNM are time-consuming or have low …

Longitudinal Analysis of Risk Factors for Clinical Outcomes of Enterobacteriaceae Meningitis/Encephalitis in Post-Neurosurgical Patients: A Comparative Cohort …

Y Shi, G Zheng, L Qian, RA Qsman, G Li… - Infection and Drug …, 2020 - Taylor & Francis
Purpose Our study is a retrospective observational study conducted in one of the largest
clinical centers of neurosurgery in China. We aimed to investigate the antimicrobial …

Impact of antibiotic therapy in the microbiological yield of healthcare–associated ventriculitis and meningitis

T Rogers, K Sok, T Erickson, E Aguilera… - Open Forum …, 2019 - academic.oup.com
The impact of antibiotic therapy on the diagnosis of healthcare–associated ventriculitis and
meningitis (HCAVM) is unknown. Antibiotics were administered before obtaining …

Healthcare-associated infections in the neurocritical care unit

KM Busl - Current neurology and neuroscience reports, 2019 - Springer
Abstract Purpose of Review This article summarizes updated data and knowledge on
healthcare-associated infections in the neurocritical care unit, with a focus on central …

Meropenem–vaborbactam for the treatment of post-neurosurgical meningitis caused by KPC producer Klebsiella pneumoniae: A case report and review of the …

LF Rezzonico, F Peracchi, M Vecchi, G Bassi, M Merli… - Antibiotics, 2024 - mdpi.com
Meningitis and ventriculitis, due to carbapenem-resistant Enterobacterales, are frequently
associated with significant morbidity and mortality. In the case of multi-drug-resistant …

Population pharmacokinetics and dosing regimen optimization of linezolid in cerebrospinal fluid and plasma of post-operative neurosurgical patients

SC Li, YF Wang, H Dong, Y Zhu, P Cao, L Meng… - Journal of …, 2023 - Elsevier
Background Linezolid is a valuable therapeutic option for infections of the central nervous
system caused by multi-drug resistant Gram-positive pathogens. Data regarding linezolid …

Profiles of central nervous system surgical site infections in endoscopic transnasal surgery exposing the intradural space

H Hasegawa, S Kiyofuji, M Umekawa, Y Shinya… - Journal of Hospital …, 2024 - Elsevier
Objective Despite its efficacy and minimal invasiveness, the clean-contaminated nature of
endoscopic transnasal surgery (ETS) may be susceptible to central nervous system surgical …