Structural proteins in severe acute respiratory syndrome coronavirus-2

S Satarker, M Nampoothiri - Archives of medical research, 2020 - Elsevier
What began with a sign of pneumonia-related respiratory disorders in China has now
become a pandemic named by WHO as Covid-19 known to be caused by Severe Acute …

The coronavirus nucleocapsid is a multifunctional protein

R McBride, M Van Zyl, BC Fielding - Viruses, 2014 - mdpi.com
The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic
RNA, interacts with the viral membrane protein during virion assembly and plays a critical …

SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs

TM Perdikari, AC Murthy, VH Ryan, S Watters… - The EMBO …, 2020 - embopress.org
Tightly packed complexes of nucleocapsid protein and genomic RNA form the core of
viruses and assemble within viral factories, dynamic compartments formed within the host …

The SARS coronavirus nucleocapsid protein–forms and functions

C Chang, MH Hou, CF Chang, CD Hsiao, T Huang - Antiviral research, 2014 - Elsevier
The nucleocapsid phosphoprotein of the severe acute respiratory syndrome coronavirus
(SARS-CoV N protein) packages the viral genome into a helical ribonucleocapsid (RNP) …

Role of host-mediated post-translational modifications (PTMs) in RNA virus pathogenesis

R Kumar, D Mehta, N Mishra, D Nayak… - International journal of …, 2020 - mdpi.com
Being opportunistic intracellular pathogens, viruses are dependent on the host for their
replication. They hijack host cellular machinery for their replication and survival by targeting …

The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D)

CL Raison, AH Miller - Molecular psychiatry, 2013 - nature.com
Given the manifold ways that depression impairs Darwinian fitness, the persistence in the
human genome of risk alleles for the disorder remains a much debated mystery …

Multiple nucleic acid binding sites and intrinsic disorder of severe acute respiratory syndrome coronavirus nucleocapsid protein: implications for ribonucleocapsid …

CK Chang, YL Hsu, YH Chang, FA Chao… - Journal of …, 2009 - Am Soc Microbiol
The nucleocapsid protein (N) of the severe acute respiratory syndrome coronavirus (SARS-
CoV) packages the viral genomic RNA and is crucial for viability. However, the RNA-binding …

[HTML][HTML] Exploiting the molecular basis of age and gender differences in outcomes of SARS-CoV-2 infections

D Mercatelli, E Pedace, P Veltri, FM Giorgi… - Computational and …, 2021 - Elsevier
Motivation: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
(coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It …

[HTML][HTML] SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins.

TM Perdikari, AC Murthy, VH Ryan, S Watters, MT Naik… - BioRxiv, 2020 - ncbi.nlm.nih.gov
Tightly packed complexes of nucleocapsid protein and genomic RNA form the core of
viruses and may assemble within viral factories, dynamic compartments formed within the …

[HTML][HTML] Viruses and the nucleolus: the fatal attraction

A Salvetti, A Greco - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2014 - Elsevier
Viruses are small obligatory parasites and as a consequence, they have developed
sophisticated strategies to exploit the host cell's functions to create an environment that …