Cancer stem cells (CSCs) or tumor initiating cells (TICs) contribute to tumorigenesis,
metastasis, recurrence and chemoresistance. CD133, a pentaspan membrane glycoprotein …

Prostate cancer is a main urological disease associated with significant morbidity and
mortality. Radical prostatectomy and radiotherapy are potentially curative for localized …

Metastasis is a major clinical obstacle responsible for the high mortality and poor prognosis
of gastric cancer (GC). MicroRNAs (miRNAs) are critical mediators of metastasis that act by …

N-cadherin has been reported to be upregulated and associated with metastasis and poor
prognosis in prostate cancer patients, however the underlying mechanism still remains …

Objectives Recently, large intergenic non-coding ribonucleic acids-RoR (linc-RoR) was
reported to regulate expression of core stem cell transcription factors (TFs), but its role in …

Micro RNA s are endogenous, small (18–25 nucleotides) non‐coding RNA s, which regulate
genes expression by directly binding to the 3′‐untranslated regions of the target …

Epithelial-to-mesenchymal transition (EMT) has been closely linked with therapy resistance
and cancer stem cells (CSCs). However, EMT pathways have proven challenging to …

Prostate cancer is the second most frequently diagnosed cancer among men worldwide,
with the estimated sixth leading cause of cancer death. Despite major advancements in …

The invasion and metastasis of tumors are triggered by an epithelial to mesenchymal
transition (EMT), which is regulated by microRNAs (miRNAs). EMT also promotes malignant …

The principal problem arising from prostate cancer (PCa) is its propensity to metastasize to
bone and the mechanism (s) need to be further elucidated. The tumor suppressor p53 plays …