Thymic epithelial tumors (TETs) are one of the rarest adult malignancies. Among TETs,
thymoma is the most predominant, characterized by a unique association with autoimmune …

Thymic epithelial tumors (TETs) are a rare and diverse group of neoplasms characterized by
distinct molecular signatures. This review delves into the complex molecular networks of …

Thymic tumors are a group of rare mediastinal malignancies that include three different
histological subtypes with completely different clinical behavior: the thymic carcinomas, the …

Introduction Thymic carcinoma (TC) is a rare cancer with a poor prognosis and limited
treatment options, especially after relapse. Methods In this open-label, two-stage …

Purpose: We report the results of a phase II, randomized, window-of-opportunity trial of
neoadjuvant durvalumab versus durvalumab plus tremelimumab followed by surgery in …

Human thymic epithelial tumors (TET) are common malignancies in the anterior
mediastinum with limited biological understanding. Here we show, by single cell analysis of …

Critical developmental “master transcription factors”(MTFs) can be subverted during
tumorigenesis to control oncogenic transcriptional programs. Current approaches to …

Thymic epithelial tumors (TETs) are one of the rarest adult malignancies in the anterior
mediastinum. Thymic carcinomas (TCs) are less prevalent among TETs, but they are more …

Introduction Thymoma and thymic carcinoma (TC) are neoplastic diseases with reported
chemosensitivity to a broad range of agents. However, because of the rarity of these …

Histone deacetylases (HDACs) are core epigenetic factors, with pivotal roles in the
regulation of various cellular procedures, and their deregulation is a major trait in the …