Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …

Patients with extensive burns rely on the use of tissue engineered skin due to a lack of
sufficient donor tissue, but it is a challenge to identify reliable and economical scaffold …

Chronic wounds have become an economic, social, and public health burden and need
advanced treatment. Platelet-rich plasma (PRP) has been used extensively in treatment of …

Elastomers are key components of many natural systems including organisms' organs. In
addition, elastomeric polymer-based materials have been used for various applications such …

Chronic skin wounds are the leading cause of nontraumatic foot amputations worldwide and
present a significant risk of morbidity and mortality due to the lack of efficient therapies. The …

Electrospinning has gained much attention in the past decade as an effective means of
generating nano-to micro-scale polymer fibers that resemble native extracellular matrix …

We obtained low and high porosity synthetic human elastin scaffolds by adapting low (1
mL/h) and high (3 mL/h) flow rates respectively during electrospinning. Physical, mechanical …

Small-diameter synthetic vascular graft materials fail to match the patency of human tissue
conduits used in vascular bypass surgery. The foreign surface retards endothelialization and …

The ultimate goal in the design of biomimetic materials for use in tissue engineering as
permanent or resorbable tissue implants is to generate biocompatible scaffolds with …

Wound healing results from complex signaling between cells and their environment in
response to injury. Fibroblasts residing within the extracellular matrix (ECM) of various …