As nanoscale extracellular vesicles, exosomes are secreted by various cell types, and they
are widely distributed in multiple biological fluids. Studies have shown that tumor-derived …

Malignant pleural mesothelioma (MPM) is a highly lethal form of pleural cancer
characterized by a scarcity of effective therapeutic interventions, resulting in unfavorable …

Aims/hypothesis Diabetic peripheral neuropathy (DPN) is one of the major complications of
diabetes, which contributes greatly to morbidity and mortality. There is currently no effective …

Altered metabolic patterns in tumor cells not only meet their own growth requirements but
also shape an immunosuppressive microenvironment through multiple mechanisms …

Background Exosomes are essential for tumor growth, metastasis, and are used as novel
signaling molecules in targeted therapies. Therefore, exosomal miRNAs can be used in new …

Cancer is one of the most difficult diseases in human society. Therefore, it is urgent for us to
understand its pathogenesis and improve the cure rate. Exosomes are nanoscale …

Exosomes are secreted by different types of cells in tumor microenvironment (TME) and
participate in multiple biological processes of tumors. Non-coding RNAs (ncRNAs) …

The pathogenesis of vascular calcification in diabetic patients remains elusive. As an
effective information transmitter, small extracellular vesicles (sEVs) carry abundant …

Lung cancer is one of the most common malignant tumors associated with cancer death;
however, the mechanisms involved in lung tumor development have not been completely …

Blood vessels deliver oxygen and nutrients that sustain tumor growth and enable the
dissemination of cancer cells to distant sites and the recruitment of intratumoral immune …