Novel roles for actin in mitochondrial fission

AL Hatch, PS Gurel, HN Higgs - Journal of cell science, 2014 - journals.biologists.com
Mitochondrial dynamics, including fusion, fission and translocation, are crucial to cellular
homeostasis, with roles in cellular polarity, stress response and apoptosis. Mitochondrial …

Functional Versatility of the CDK Inhibitor p57Kip2

J Creff, A Besson - Frontiers in cell and developmental biology, 2020 - frontiersin.org
The cyclin/CDK inhibitor p57Kip2 belongs to the Cip/Kip family, with p21Cip1 and p27Kip1,
and is the least studied member of the family. Unlike the other family members, p57Kip2 has …

LIM kinases, LIMK1 and LIMK2, are crucial node actors of the cell fate: molecular to pathological features

E Villalonga, C Mosrin, T Normand, C Girardin… - Cells, 2023 - mdpi.com
LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2) are serine/threonine and tyrosine kinases
and the only two members of the LIM kinase family. They play a crucial role in the regulation …

[PDF][PDF] Down‐regulation of the cyclin‐dependent kinase inhibitor p57 is mediated by Jab1/Csn5 in hepatocarcinogenesis

H Guo, L Jing, Y Cheng, V Atsaves, Y Lv, T Wu… - …, 2016 - Wiley Online Library
Down‐regulation of p57 (KIP2) cyclin‐dependent kinase inhibitors accelerates the growth
and invasion of hepatocellular carcinoma (HCC), suggesting that p57 may play an important …

The long non-coding RNA Kcnq1ot1 controls maternal p57 expression in muscle cells by promoting H3K27me3 accumulation to an intragenic MyoD-binding region

O Andresini, MN Rossi, F Matteini, S Petrai… - Epigenetics & …, 2019 - Springer
Background The cell-cycle inhibitor p57 kip2 plays a critical role in mammalian development
by coordinating cell proliferation and differentiation in many cell types. p57 kip2 expression …

Research progress of mitochondria and cytoskeleton crosstalk in tumour development

Y Ji, Y Lin, J He, Y Xie, W An, X Luo, X Qiao… - Biochimica et Biophysica …, 2024 - Elsevier
During tumour progression, organelle function undergoes dramatic changes, and crosstalk
among organelles plays a significant role. Crosstalk between mitochondria and other …

Cellular response upon stress: p57 contribution to the final outcome

MN Rossi, F Antonangeli - Mediators of inflammation, 2015 - Wiley Online Library
Progression through the cell cycle is one of the most important decisions during the life of a
cell and several kinds of stress are able to influence this choice. p57 is a cyclin‐dependent …

Effects of EHD2 interference on migration of esophageal squamous cell carcinoma

M Li, X Yang, J Zhang, H Shi, Q Hang, X Huang, G Liu… - Medical Oncology, 2013 - Springer
C-Terminal EH domain-containing protein 2 (EHD2) of the EHD family is associated with
plasma membrane. We investigated the expression of EHD2 in human esophageal …

[HTML][HTML] p57Kip2 Phosphorylation Modulates Its Localization, Stability, and Interactions

E Stampone, D Bencivenga, L Dassi, S Sarnelli… - International Journal of …, 2024 - mdpi.com
p57Kip2 is a member of the cyclin-dependent kinase (CDK) Interacting Protein/Kinase
Inhibitory Protein (CIP/Kip) family that also includes p21Cip1/WAF1 and p27Kip1. Different …

Cytoskeleton dysfunction of motor neuron in spinal muscular atrophy

T Shi, Z Zhou, T Xiang, Y Suo, X Shi, Y Li, P Zhang… - Journal of …, 2025 - Springer
Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by deletions or
mutations of survival of motor neuron 1 (SMN1) gene. To date, the mechanism of selective …