Comparison of preprint postings of randomized clinical trials on COVID-19 and corresponding published journal articles: a systematic review
AD Bai, Y Jiang, DL Nguyen, CKL Lo… - JAMA Network …, 2023 - jamanetwork.com
Importance Randomized clinical trials (RCTs) on COVID-19 are increasingly being posted
as preprints before publication in a scientific, peer-reviewed journal. Objective To assess …
as preprints before publication in a scientific, peer-reviewed journal. Objective To assess …
Repurposing of chemotherapeutics to combat COVID-19
S Nandi, BS Nayak, MK Khede… - Current Topics in …, 2022 - benthamdirect.com
Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) is a novel strain of SARS
coronavirus. The COVID-19 disease caused by this virus was declared a pandemic by the …
coronavirus. The COVID-19 disease caused by this virus was declared a pandemic by the …
A Comprehensive Biological and Synthetic Perspective on 2-Deoxy-d-Glucose (2-DG), A Sweet Molecule with Therapeutic and Diagnostic Potentials
YS Wijayasinghe, MP Bhansali… - Journal of Medicinal …, 2022 - ACS Publications
Glucose, the primary substrate for ATP synthesis, is catabolized during glycolysis to
generate ATP and precursors for the synthesis of other vital biomolecules. Opportunistic …
generate ATP and precursors for the synthesis of other vital biomolecules. Opportunistic …
Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs
JS Jutzi, AE Marneth, M Ciboddo… - Blood, The Journal …, 2022 - ashpublications.org
Calreticulin (CALR) mutations are frequent, disease-initiating events in myeloproliferative
neoplasms (MPNs). Although the biological mechanism by which CALR mutations cause …
neoplasms (MPNs). Although the biological mechanism by which CALR mutations cause …
Modulation of pentose phosphate pathway augments the efficacy of 2-deoxy-D-glucose in COVID-19 management
S Chopra, A Nair, N Sharma, V Jain, RK Sharma - Stem Cells, 2024 - Elsevier
The outbreak of pandemic due to the severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2), also known as coronavirus disease 2019 (COVID-19), has brought an …
(SARS-CoV-2), also known as coronavirus disease 2019 (COVID-19), has brought an …
2-Deoxy-D-Glucose as a Potential Antiviral and Anti-COVID-19 Drug
P Santhoshkumar, ASA Poorani… - 2-Deoxy-D-Glucose …, 2024 - benthamdirect.com
The search for effective therapeutics has been unyielding in the relentless battle against the
COVID-19 pandemic. A potential drug candidate is 2-deoxyD-glucose (2-DG), which has …
COVID-19 pandemic. A potential drug candidate is 2-deoxyD-glucose (2-DG), which has …
Augmented glucose dependency of autoreactive B cells provides a treatment target for lupus
JJ Wilson, J Wei, AR Daamen, JD Sears, E Bechtel… - bioRxiv, 2022 - biorxiv.org
Heightened glycolysis is inherent to immune/inflammatory disorders, but little is known of its
role in the pathogenesis of systemic lupus erythematosus (lupus). Here, we profile key …
role in the pathogenesis of systemic lupus erythematosus (lupus). Here, we profile key …