Ovarian cancer: biomarkers and targeted therapy

MR Radu, A Prădatu, F Duică, R Micu, SM Creţoiu… - Biomedicines, 2021 - mdpi.com
Ovarian cancer is one of the most common causes of death in women as survival is highly
dependent on the stage of the disease. Ovarian cancer is typically diagnosed in the late …

A bioinformatics analysis: ZFHX4 is associated with metastasis and poor survival in ovarian cancer

S Zong, P Xu, Y Xu, Y Guo - Journal of Ovarian Research, 2022 - Springer
Background Metastasis was the major cause of the high mortality in ovarian cancer.
Although some mechanisms of metastasis in ovarian cancer were proposed, few have been …

Analysis of the mutational landscape of osteosarcomas identifies genes related to metastasis and prognosis and disrupted biological pathways of immune response …

SF Pires, JS Barros, SS Costa, GB Carmo… - International Journal of …, 2023 - mdpi.com
Osteosarcoma (OS) is the most prevalent type of bone tumor, but slow progress has been
achieved in disentangling the full set of genomic events involved in its initiation and …

[HTML][HTML] Effective treatment of anlotinib in giant delayed pulmonary metastasis of osteosarcoma: a case report and literature review

ZY Long, Y Lu, M Li, G Chen, L Shi… - Annals of Palliative …, 2021 - apm.amegroups.org
Tumor relapse and pulmonary metastasis, especially unresectable lesions, are the major
cause of poor prognosis of patients with osteosarcoma. Anlotinib, a novel small-molecule …

Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene underlies a neurodevelopmental disorder

PBM Del Rocío, MP Bralo, M Vanhooydonck… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
8q21. 11 microdeletions encompassing the gene encoding transcription factor ZFHX4, have
previously been associated by us with a syndromic form of intellectual disability, hypotonia …

The prevalence, associated factors for lung metastases development and prognosis in ovarian serous cancer based on SEER database

C Cao, X Yang - Technology in Cancer Research & …, 2020 - journals.sagepub.com
Ovarian carcinoma (OC) is one of the 3 most common gynecological malignancies, and the
prognosis of patients with lung metastasis was the worst. SEER documented OC patients …

Predictive value of ZFHX4 mutation for the efficacy of immune checkpoint inhibitors in non-small cell lung cancer and melanoma

C Fu, H Gu, L Sun, Z Wang, Q Zhang, N Luo… - Investigational New …, 2024 - Springer
Studies have shown that the Zinc finger homeobox 4 (ZFHX4) might be a factor in the
prognosis of malignancies. However, little is known about the association between the …

Long non-coding RNA ZFHX4-AS1 Upregulates the Neural Differentiation-related Gene ZFHX4 and thereby Promotes SOX2 Expression to Accelerate Glioma …

H Yan, Y Shi, Q Jin, K Guo, S Zhu, S Zhang, Z Zhao - 2023 - researchsquare.com
Background ZFHX4-AS1 is a recently discovered long noncoding RNA, and whether it is
involved in glioma progression is unclear. Results We found that ZFHX4-AS1 and its nearby …

A bioinformatics analysis: ZFHX4 promotes metastasis in ovarian cancer by modulating epithelial-mesenchymal transition and remodeling extracellular matrix

S Zong, P Xu, Y Xu, Y Guo - 2022 - researchsquare.com
Background Ovarian cancer is a highly malignant gynecological tumor with high mortality
worldwide. The poor prognosis mainly results from extensive metastasis at the time of …

[PDF][PDF] Ovarian Cancer: Biomarkers and Targeted Therapy. Biomedicines 2021, 9, 693

MR Radu, A Pradatu, F Duica, R Micu, SM Cretoiu… - 2021 - academia.edu
Ovarian cancer is one of the most common causes of death in women as survival is highly
dependent on the stage of the disease. Ovarian cancer is typically diagnosed in the late …